Oncocytic Nodule/Hürtle Cell Tumors

  • Arne Heilo
  • Eva Sigstad
  • Krystyna Grøholt


Formerly oncocytic lesions were regarded as a definite entity, but this classification is no longer used. Cytopathologists define oncocytic cells as follows: “Oncocytic follicular cells in the thyroid, known as Hürtle cells, are characterized by large size, polygonal to square shape, distinct cell borders, voluminous granular and eosinophilic cytoplasm, and a large, often hyperchromatic nucleus with prominent cherry pink macronucleoli”. The proliferation of oncocytes gives rise to hyperplastic and neoplastic nodules. Oncocytic cells may behave as follicular carcinomas including capsular and vascular invasion, or they may behave as papillary carcinomas showing papillary architecture.


Thyroid Carcinoma Papillary Thyroid Carcinoma Papillary Carcinoma Eosinophilic Cytoplasm Follicular Thyroid Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+ Business Media, LLC  2010

Authors and Affiliations

  1. 1.Department of RadiologyOslo University Hospital Section The Norwegian Radium HospitalOsloNorway
  2. 2.Department of PathologyOslo University Hospital Section The Norwegian Radium HospitalOsloNorway

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