Technologies for the Generation of Human Antibodies
Over the course of the last 15 years antibodies as drugs have come into their own—there are now 26 therapeutic antibodies on the market in the United States. With the passing of time, new technological developments together with competition for finite markets have continually raised the bar for the specifications of newly introduced antibodies. Our intent in this review is to provide a historical perspective on the technologies that have generated the fully human antibody drugs currently on the market as well as to impart a sense of excitement for the technologies in development that will provide the antibody drugs of the future.
KeywordsLight Chain Phage Display Somatic Hypermutation Phage Display Library Antibody Library
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