Follicular carcinoma (FC) is the second most common malignancy of the thyroid after papillary thyroid carcinoma (PTC), representing approximately 15% of all thyroid carcinomas. Most FCs are minimally invasive and are categorized as well-differentiated tumors that have an excellent prognosis. A small subset of FCs, however, are widely invasive carcinomas (i.e., grossly recognizable as carcinomas) with a much more aggressive clinical course. In addition, the classic subtype of poorly differentiated thyroid carcinoma is insular carcinoma, a rare, aggressive follicular-derived tumor.
KeywordsIodine Adenoma Calcitonin Acne Hyperthyroidism
- Greaves TS, Olvera M, Florentine BD, et al. Follicular lesions of thyroid: a 5-year fine-needle aspiration experience. Cancer Cytopathol 2000;90:335–341.Google Scholar