Sedation and Analgesia

  • Paul Ellis Marik


Anxiety is an almost universal feature of ICU patients. Clinically significant anxiety has been reported in up to 70% of ICU patients. Severe anxiety is not limited to mechanically ventilated patients; indeed Treggiari-Venzi and colleagues demonstrated that up to 30% of non-intubated SICU patients had severe anxiety.1 Consequently, sedation is an integral component of the management of the ICU patient. The primary objective of sedation is to allay anxiety, enhance patient comfort, promote sleep, and facilitate mechanical ventilation. The desirable level of sedation/hypnosis will depend in large part upon the patient’s acute disease process as well as the need for mechanical ventilation. However, the ideal level of sedation is one from which the patient can be easily aroused with maintenance of the normal sleep–wake cycle.


Neuromuscular Blockade Deep Sedation Severe Anxiety Alcohol Withdrawal Syndrome Sedation Scale 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care MedicineEastern Virginia Medical SchoolNorfolkUSA

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