Posterior reversible encephalopathy syndrome (PRES), first described by Hinchey and colleagues in 1996, is a clinico-neuro-radiological entity characterized by headache, vomiting, altered mental status, blurred vision, and seizures with neuroimaging studies, demonstrating white–gray matter edema involving predominantly the posterior region of the brain.1 PRES is most commonly associated with pre-eclampsia, hypertensive encephalopathy, and immunosuppressive/cytotoxic drugs.2–4 One of the distinctive characteristics of PRES is the reversibility of the clinical and radiological abnormalities once treatment is instituted. Most patients usually make a complete recovery within few weeks. A delay in the recognition and treatment of the syndrome may result in permanent neurological sequela.
Status Epilepticus Posterior Reversible Encephalopathy Syndrome Refractory Status Epilepticus Hypertensive Encephalopathy Pyrimidine Nucleoside
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Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334:494–500.PubMedCrossRefGoogle Scholar
Servillo G, Bifulco F, De Robertis E, et al. Posterior reversible encephalopathy syndrome in intensive care medicine. Intensive Care Med. 2007;33:230–236.PubMedCrossRefGoogle Scholar
Bartynski WS. Posterior reversible encephalopathy syndrome, part 1: fundamental imaging and clinical features. AJNR. 2008;29:1036–1042.PubMedCrossRefGoogle Scholar
Gocmen R, Ozgen B, Oguz KK. Widening the spectrum of PRES: series from a tertiary care center. Eur J Radiol. 2007;62:454–459.PubMedCrossRefGoogle Scholar
Bartynski WS, Boardman JF, Zeigler ZR, et al. Posterior reversible encephalopathy syndrome in infection, sepsis, and shock. AJNR. 2006;27:2179–2190.PubMedGoogle Scholar
Servillo G, Striano P, Striano S, et al. Posterior reversible encephalopathy syndrome (PRES) in critically ill obstetric patients. Intensive Care Med. 2003;29:2323–2326.PubMedCrossRefGoogle Scholar
Celik M, Forta H, Dalkilic T, et al. MRI reveals reversible lesions resembling posterior reversible encephalopathy in porphyria. Neuroradiology. 2002;44:839–841.PubMedCrossRefGoogle Scholar
Chawla R, Smith D, Marik PE. Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure treated by induced hypothermia and dialysis: a case report. J Med Case Rep. 2009;3:6623.Google Scholar
Baizabal-Carvallo JF, Barragan-Campos HM, Padilla-Aranda HJ, et al. Posterior reversible encephalopathy syndrome as a complication of acute lupus activity. Clin Neurol Neurosurg. 2009;111:359–363.PubMedCrossRefGoogle Scholar
McKinney AM, Short J, Truwit CL, et al. Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings. AJR. 2007;189:904–912.PubMedCrossRefGoogle Scholar
Casey SO, Sampaio RC, Michel E, et al. Posterior reversible encephalopathy syndrome: utility of fluid-attenuated inversion recovery MR imaging in the detection of cortical and subcortical lesions. AJNR Am J Neuroradiol. 2000;21:1199–1206.PubMedGoogle Scholar