Posterior reversible encephalopathy syndrome (PRES), first described by Hinchey and colleagues in 1996, is a clinico-neuro-radiological entity characterized by headache, vomiting, altered mental status, blurred vision, and seizures with neuroimaging studies, demonstrating white–gray matter edema involving predominantly the posterior region of the brain.1 PRES is most commonly associated with pre-eclampsia, hypertensive encephalopathy, and immunosuppressive/cytotoxic drugs.2–4 One of the distinctive characteristics of PRES is the reversibility of the clinical and radiological abnormalities once treatment is instituted. Most patients usually make a complete recovery within few weeks. A delay in the recognition and treatment of the syndrome may result in permanent neurological sequela.


Status Epilepticus Posterior Reversible Encephalopathy Syndrome Refractory Status Epilepticus Hypertensive Encephalopathy Pyrimidine Nucleoside 
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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care MedicineEastern Virginia Medical SchoolNorfolkUSA

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