Multi-organ Dysfunction Syndrome

  • Paul Ellis Marik


With the widespread use of advanced technology for organ support, patients rarely die from their presenting disease but rather from its pathophysiological consequences, namely the sequential dysfunction and failure of several organ systems. This syndrome has been called “multi-system organ failure” (MSOF), “multiple organ system failure” (MOSF), and more recently “multi-organ dysfunction syndrome” (MODS). MODS has an extraordinarily high mortality and, for many patients, the support of this syndrome does not improve survival but rather prolongs the dying process.


Organ Failure Circulatory Shock Multiple Organ Dysfunction Score Multiple Organ System Failure Splanchnic Ischemia 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Division of Pulmonary and Critical Care MedicineEastern Virginia Medical SchoolNorfolkUSA

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