Skip to main content
SpringerLink
Log in

Stimuli-Responsive Hydrogels and Their Application to Functional Materials

  • Chapter
  • First Online:
Biomedical Applications of Hydrogels Handbook

Abstract

Many kinds of stimuli-responsive polymer gels that respond to the change in their surroundings such as solvent composition, temperature, pH, and supply of electric field have been developed. They are of interest as intelligent (or smart, biomimetic) materials which have sensor, processor, and actuator functions. This article is related to stimuli-­responsive gels and their application for bio- or biomimetic materials designed as self-oscillating gels.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Tanaka T (1978) Phys Rev Lett 4:820; Tanaka T (1981) Sci Am 244:124

    Google Scholar 

  2. Osada Y, Okuzaki H, Hori H (1992) Nature 355:242

    CAS  Google Scholar 

  3. Kokufuta E, Zhang YQ, Tanaka T (1994) J Biomater Sci Polym Ed 6:35

    CAS  Google Scholar 

  4. Hirai T, Nemoto H, Hirai M, Hayashi S (1994) J Appl Polym Sci 53:79

    CAS  Google Scholar 

  5. Fukushima T, Asaka K, Kosaka A, Aida T (2005) Angew Chem Int Ed 44:2410

    CAS  Google Scholar 

  6. Asaka K, Oguro K (2000) J Electroanal Chem 480:186

    CAS  Google Scholar 

  7. Zrinyi M, Szabo D, Filipcsei G, Feher J (2002) In: Osada Y, Khokhlov AR (eds) Polymer gels and networks. Marcel Dekker, New York, pp 309–355

    Google Scholar 

  8. Osada Y, Matsuda A (1995) Nature 376:219

    CAS  Google Scholar 

  9. Weissman JM, Sunkara HB, Tse AS, Asher SA (1996) Science 274:959

    CAS  Google Scholar 

  10. Holtz JH, Asher SA (1997) Nature 389:829

    CAS  Google Scholar 

  11. Holtz JH, Holtz JSW, Munro CH, Asher SA (1998) Anal Chem 70:780

    CAS  Google Scholar 

  12. Hu ZB, Lu XH, Gao J (2001) Adv Mater 13:1708

    CAS  Google Scholar 

  13. Takeoka Y, Watanabe M (2003) Adv Mater 15:199

    CAS  Google Scholar 

  14. Takeoka Y, Watanabe M (2002) Langmuir 18:5977

    CAS  Google Scholar 

  15. Nakayama D, Takeoka Y, Watanabe M, Kataoka K (2003) Angew Chem Int Ed 42:4197

    CAS  Google Scholar 

  16. Akashi R, Tsutsui H, Komura A (2002) Adv Mater 14:1808

    CAS  Google Scholar 

  17. Komiyama M, Takeuchi T, Mukawa T, Asanuma H (2003) Molecular imprinting – from fundamentals to applications. Wiley-VCH, Weinheim

    Google Scholar 

  18. Vlatakis G, Andersson LI, Muller R, Mosbach K (1993) Nature 361:645

    CAS  Google Scholar 

  19. Oya T, Enoki T, Grosberg AY, Masamune S, Sakiyama T, Takeoka Y, Tanaka K, Wang G, Yilmaz Y, Feld MS, Dasari R, Tanaka T (1999) Science 286:1543

    CAS  Google Scholar 

  20. Miyata T, Asami N, Uragami T (1999) Nature 399:766

    CAS  Google Scholar 

  21. Miyata T, Jige M, Nakaminami T, Uragami T (2006) Proc Natl Acad Sci USA 103:1190

    CAS  Google Scholar 

  22. Hoffman AS (2002) Adv Drug Deliv Rev 43:3

    Google Scholar 

  23. Okano T (ed) (1998) Biorelated polymers and gels – controlled release and applications in biomedical engineering. Academic Press, San Diego

    Google Scholar 

  24. Yoshida R, Okano T, Sakurai Y, Sakai K (1994) J Biomater Sci Polym Ed 6:585

    CAS  Google Scholar 

  25. Makino K, Mack EJ, Okano T, Kim SW (1990) J Control Release 12:235

    CAS  Google Scholar 

  26. Kost J, Horbett TA, Ratner BD, Singh MJ (1985) Biomed Mater Res 19:1117

    CAS  Google Scholar 

  27. Ishihara K, Kobayashi M, Shinohara J (1983) Makromol Chem Rapid Commun 4:327

    CAS  Google Scholar 

  28. Ito Y, Casolaro M, Kono K, Imanishi Y (1989) J Control Release 10:195

    CAS  Google Scholar 

  29. Kataoka K, Miyazaki H, Bunya M, Okano T, Sakurai Y (1998) J Am Chem Soc 120:12694

    CAS  Google Scholar 

  30. Matsumoto A, Yoshida R, Kataoka K (2004) Biomacromolecules 5:1038

    CAS  Google Scholar 

  31. Yoshida R, Sakai K, Okano T, Sakurai Y (1993) Adv Drug Deliv Rev 11:85

    CAS  Google Scholar 

  32. Kikuchi A, Okano T (2002) Adv Drug Deliv Rev 54:53

    CAS  Google Scholar 

  33. Kiser RF, Wilson G, Needham D (1998) Nature 394:459

    CAS  Google Scholar 

  34. Takei YG, Aoki T, Sanui K, Ogata N, Sakurai Y, Okano T (1994) Macromolecules 27:6163

    CAS  Google Scholar 

  35. Yakushiji T, Sakai K, Kikuchi A, Aoyagi T, Sakurai Y, Okano T (1998) Langmuir 14:4657

    CAS  Google Scholar 

  36. Kanazawa H, Yamamoto K, Matsushima Y, Takai N, Kikuchi A, Sakurai Y, Okano T (1996) Anal Chem 68:100; ibid 69:823

    CAS  Google Scholar 

  37. Kanazawa H, Matsushima Y, Okano T (1998) Trends Anal Chem 17:435

    CAS  Google Scholar 

  38. Kanazawa H, Yamamoto K, Kashiwase Y, Matsushima Y, Takai N, Kikuchi A, Sakurai Y, Okano T (1997) J Pharm Biomed Anal 15:1545

    CAS  Google Scholar 

  39. Yoshizako K, Akiyama Y, Yamanaka H, Shinohara Y, Hasegawa Y, Carredano E, Kikuchi A, Okano T (2002) Anal Chem 74:4160

    CAS  Google Scholar 

  40. Yamanaka H, Yoshizako K, Akiyama Y, Sota H, Hasegawa Y, Shinohara Y, Kikuchi A, Okano T (2003) Anal Chem 75:1658

    CAS  Google Scholar 

  41. Kobayashi J, Kikuchi A, Sakai K, Okano T (2003) Anal Chem 73:2027

    Google Scholar 

  42. Sakamaoto C, Okada Y, Kanazawa H, Ayano E, Nishimura T, Ando M, Kikuchi A, Okano T (2004) J Chromatogr A 103:247

    Google Scholar 

  43. Vacanti JP (1988) Arch Surg 123:545

    CAS  Google Scholar 

  44. Langer R, Vacanti JP (1993) Science 260:920

    CAS  Google Scholar 

  45. Vacanti JP, Langer R (1999) Lancet 354(Suppl 1):S132

    Google Scholar 

  46. Shinoka T, Breuer CK, Tanel RE, Zund G, Miura T, Ma PX, Langer R, Vacanti JP, Mayer JE Jr (1995) Ann Thorac Surg 60:S513

    CAS  Google Scholar 

  47. Puelacher WC, Vacanti JP, Ferraro NF, Schloo B, Vacanti CA (1996) Int J Oral Maxillofac Surg 25:223

    CAS  Google Scholar 

  48. Vacanti CA, Langer R, Schloo B, Vacanti JP (1991) Plast Reconstr Surg 88:753

    CAS  Google Scholar 

  49. Cao Y, Vacanti JP, Paige KT, Upton J, Vacanti CA (1997) Plast Reconstr Surg 100:297

    CAS  Google Scholar 

  50. Yamada N, Okano T, Sakai H, Karikusa F, Sawasaki Y, Sakurai Y (1990) Makromol Chem Rapid Commun 11:571

    CAS  Google Scholar 

  51. Okano T, Yamada N, Sakai H, Sakurai Y (1993) J Biomed Mater Res 27:1243

    CAS  Google Scholar 

  52. Kushida A, Yamato M, Konno C, Kikuchi A, Sakurai Y, Okano T (1999) J Biomed Mater Res 45:355

    CAS  Google Scholar 

  53. Hirose M, Kwon OH, Yamato M, Kikuchi A, Okano T (2000) Biomacromolecules 1:377

    CAS  Google Scholar 

  54. Nandkumar MA, Yamato M, Kushida A, Konno C, Hirose M, Kikuchi A, Okano T (2002) Biomaterials 23:1121

    CAS  Google Scholar 

  55. Harimoto M, Yamato M, Hirose M, Takahashi C, Isoi Y, Kikuchi A, Okano T (2002) J Biomed Mater Res 62:464

    CAS  Google Scholar 

  56. Shimizu T, Yamato M, Isoi Y, Akutsu T, Setomaru T, Abe K, Kikuchi A, Umezu M, Okano T (2002) Circ Res 90:e40

    CAS  Google Scholar 

  57. Nishida K, Yamato M, Hayashida Y, Watanabe K, Maeda N, Watanabe H, Yamamoto K, Nagai S, Kikuchi A, Tano Y, Okano T (2004) Transplantation 77:379

    Google Scholar 

  58. Nishida K, Yamato M, Hayashida Y, Watanabe K, Yamamoto K, Adachi E, Nagai S, Kikuchi A, Maeda N, Watanabe H, Okano T, Tano Y (2004) N Engl J Med 351:1187

    CAS  Google Scholar 

  59. Shiroyanagi Y, Yamato M, Yamazaki Y, Toma H, Okano T (2004) BJU Int 93:1069

    CAS  Google Scholar 

  60. Hasegawa M, Yamato M, Kikuchi A, Okano T, Ishikawa I (2005) Tissue Eng 11:469

    CAS  Google Scholar 

  61. Yamato M, Utsumi M, Kushida A, Konno C, Kikuchi A, Okano T (2001) Tissue Eng 7:473

    CAS  Google Scholar 

  62. Ebara M, Yamato M, Aoyagi T, Kikuchi A, Sakai K, Okano T (2004) Biomacromolecules 5:505

    CAS  Google Scholar 

  63. Ebara M, Yamato M, Aoyagi T, Kikuchi A, Sakai K, Okano T (2004) Tissue Eng 10:1125

    CAS  Google Scholar 

  64. Yamato M, Konno C, Utsumi M, Kikuchi A, Okano T (2002) Biomaterials 23:561

    CAS  Google Scholar 

  65. Yamato M, Kwon OH, Hirose M, Kikuchi A, Okano T (2001) J Biomed Mater Res 55:137

    CAS  Google Scholar 

  66. Tsuda Y, Kikuchi A, Yamato M, Sakurai Y, Umezu M, Okano T (2004) J Biomed Mater Res 69A:70

    CAS  Google Scholar 

  67. Okumura Y, Ito K (2001) Adv Mater Des 13:485

    CAS  Google Scholar 

  68. Gong JP, Katsuyama Y, Kurokawa T, Osada Y (2003) Adv Mater 15:1155

    CAS  Google Scholar 

  69. Haraguchi K, Takehisa T (2002) Adv Mater 14:1120

    CAS  Google Scholar 

  70. Yoshida R, Uchida K, Kaneko Y, Sakai K, Kikuchi A, Sakurai Y, Okano T (1995) Nature 374:240

    CAS  Google Scholar 

  71. Kaneko Y, Sakai K, Kikuchi A, Yoshida R, Sakurai Y, Okano T (1995) Macromolecules 28:7717

    CAS  Google Scholar 

  72. Kaneko Y, Nakamura S, Sakai K, Aoyagi T, Kikuchi A, Sakurai Y, Okano T (1998) Macromolecules 31:6099

    CAS  Google Scholar 

  73. Hu Z, Chen Y, Wang C, Zheng Y, Li Y (1998) Nature 393:149

    CAS  Google Scholar 

  74. Chen G, Imanishi Y, Ito Y (1998) Macromolecules 31:4379

    CAS  Google Scholar 

  75. Beebe DJ, Moore JS, Bauer JM, Yu Q, Liu RH, Devadoss C, Jo BH (2000) Nature 404:588

    CAS  Google Scholar 

  76. Eddington DT, Beebe DJ (2004) Adv Drug Deliv Rev 56:199

    CAS  Google Scholar 

  77. Watanabe T, Akiyama M, Totani K, Kuebler SM, Stellacci F, Wenseleers W, Braun K, Marder SR, Perry JW (2002) Adv Funct Mater 12:611

    CAS  Google Scholar 

  78. Zaikin AN, Zhabotinsky AM (1970) Nature 225:535

    CAS  Google Scholar 

  79. Field RJ, Burger M (eds) (1985) Oscillations and traveling waves in chemical systems. Wiley, New York

    Google Scholar 

  80. Epstein IR, Pojman JA (1998) An introduction to nonlinear chemical dynamics: oscillations, waves, patterns, and chaos. Oxford University Press, New York

    Google Scholar 

  81. Yoshida R, Takahashi T, Yamaguchi T, Ichijo H (1996) J Am Chem Soc 118:5134

    CAS  Google Scholar 

  82. Yoshida R, Takahashi T, Yamaguchi T, Ichijo H (1997) Adv Mater 9:175

    CAS  Google Scholar 

  83. Yoshida R (2008) Bull Chem Soc Jpn 81:676

    CAS  Google Scholar 

  84. Yoshida R, Tanaka M, Onodera S, Yamaguchi T, Kokufuta E (2000) J Phys Chem A 104:7549

    CAS  Google Scholar 

  85. Yoshida R, Takei K, Yamaguchi T (2003) Macromolecules 36:1759

    CAS  Google Scholar 

  86. Ito Y, Nogawa M, Yoshida R (2003) Langmuir 19:9577

    CAS  Google Scholar 

  87. Maeda S, Hara Y, Yoshida R, Hashimoto S (2008) Angew Chem Int Ed 47:6690

    CAS  Google Scholar 

  88. Sasaki S, Koga S, Yoshida R, Yamaguchi T (2003) Langmuir 19:5595

    CAS  Google Scholar 

  89. Amemiya T, Ohmori T, Yamaguchi T (2000) J Phys Chem 104:336

    CAS  Google Scholar 

  90. Yoshida R, Sakai T, Tabata O, Yamaguchi T (2002) Sci Technol Adv Mater 3:95

    CAS  Google Scholar 

  91. Takeoka Y, Watanabe M, Yoshida R (2003) J Am Chem Soc 125:13320

    CAS  Google Scholar 

  92. Shinohara S, Seki T, Sakai T, Yoshida R, Takeoka Y (2008) Chem Commun 39:4735

    Google Scholar 

  93. Shinohara S, Seki T, Sakai T, Yoshida R, Takeoka Y (2008) Angew Chem Int Ed 47:9039

    CAS  Google Scholar 

  94. Maeda S, Hara Y, Sakai T, Yoshida R, Hashimoto S (2007) Adv Mater 19:3480

    CAS  Google Scholar 

  95. Maeda S, Hara Y, Yoshida R, Hashimoto S (2008) Macromol Rapid Commun 29:401

    CAS  Google Scholar 

  96. Murase Y, Maeda S, Hashimoto S, Yoshida R (2009) Langmuir 25:483

    CAS  Google Scholar 

  97. Tabata O, Hirasawa H, Aoki S, Yoshida R, Kokufuta E (2002) Sens Actuators A 95:234

    CAS  Google Scholar 

  98. Tateyama S, Shibuta Y, Yoshida R (2008) J Phys Chem B 112:1777

    CAS  Google Scholar 

  99. Yoshida R, Sakai T, Ito S, Yamaguchi T (2002) J Am Chem Soc 124:8095

    CAS  Google Scholar 

  100. Ito Y, Hara Y, Uetsuka H, Hasuda H, Onishi H, Arakawa H, Ikai A, Yoshida R (2006) J Phys Chem B 110:5170

    CAS  Google Scholar 

  101. Suzuki D, Sakai T, Yoshida R (2008) Angew Chem Int Ed 47:917

    CAS  Google Scholar 

  102. Suzuki D, Yoshida R (2008) Macromolecules 41:5830

    CAS  Google Scholar 

  103. Suzuki D, Yoshida R (2008) J Phys Chem B 112:12618

    CAS  Google Scholar 

  104. Sakai T, Yoshida R (2004) Langmuir 20:1036

    CAS  Google Scholar 

  105. Sakai T, Takeoka Y, Seki T, Yoshida R (2007) Langmuir 23:8651

    CAS  Google Scholar 

  106. Hara Y, Yoshida R (2005) J Phys Chem B 109:9451

    CAS  Google Scholar 

  107. Hara Y, Yoshida R (2005) Langmuir 21:9773

    CAS  Google Scholar 

  108. Hara Y, Sakai T, Maeda S, Hashimoto S, Yoshida R (2005) J Phys Chem B 109:23316

    CAS  Google Scholar 

  109. Hara Y, Yoshida R (2008) J Phys Chem B 112:8427

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan

    Ryo Yoshida

  2. Institute of Advanced Biomedical Engineering and Science, TWIns., Tokyo Women’s Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666, Japan

    Teruo Okano

Authors
  1. Ryo Yoshida
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Teruo Okano
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Teruo Okano .

Editor information

Editors and Affiliations

  1. Virginia Commonwealth University, Richmond, 23284, Virgin Islands, USA

    Raphael M. Ottenbrite

  2. Dept. Biomedical Engineering, Purdue University, West Lafayette, 47907-1296, Indiana, USA

    Kinam Park

  3. Tokyo Women's Medical College, Kawada-cho Ichigaya 8-1, Tokyo, 162-8666, Japan

    Teruo Okano

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Yoshida, R., Okano, T. (2010). Stimuli-Responsive Hydrogels and Their Application to Functional Materials. In: Ottenbrite, R., Park, K., Okano, T. (eds) Biomedical Applications of Hydrogels Handbook. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5919-5_2

Download citation

Publish with us

Policies and ethics

Search

Navigation