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Patient-Specific Hemodynamic Analysis for Proximal Protection in Carotid Angioplasty

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Computational Biomechanics for Medicine

Abstract

Embolic protective devices (EPD) are used in carotid angioplasty to reduce or prevent embolic debris from entering the brain and causing procedure-related strokes. In this chapter we analyze a proximal protection mechanism of EPD that performs cerebral protection by external and common carotid artery occlusion. The mathematical model we use is a one-dimensional (1D) equation system governing blood flow. This system is applied to a patient-specific arterial tree constructed from a 3D computed tomography angiography (CTA) image. We simulate the blood flow in both normal and procedural conditions. Wherever possible we compare our computation results with laboratory or previously published measurements and our model agrees with these data.

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Acknowledgments

We thank Prof. Juan Parodi of University of Miami for his explanation of the PAES procedure in e-mail transactions; we also thank the comments given by Mr. Gary Chaisson of Cardiovascular Institute of the South (Louisiana) regarding the procedure. We are grateful for the help from Dr. Kumar Mithraratne on 1D flow modeling.

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Correspondence to Harvey Ho .

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Ho, H., Ladd, D., Holden, A., Hunter, P. (2010). Patient-Specific Hemodynamic Analysis for Proximal Protection in Carotid Angioplasty. In: Miller, K., Nielsen, P. (eds) Computational Biomechanics for Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5874-7_5

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  • DOI: https://doi.org/10.1007/978-1-4419-5874-7_5

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-5873-0

  • Online ISBN: 978-1-4419-5874-7

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