Potential Impact of Genomic Information on Childhood Sibling Relationships

  • Joanna Fanos
  • Lori Wiener
  • Tara Brennan
Part of the Issues in Clinical Child Psychology book series (ICCP)


With the tremendous growth and excitement in the field of genomics, there is reason to be hopeful that evidence-based data on the experience of siblings will follow. As the field prospers, sibling relationships will be challenged by major issues, including differential interest in seeking carrier, pre-symptomatic and susceptibility testing, the handling of differential genomic data between sibling dyads, and the resultant apprehension and mastery. The potential impact of genomic information on childhood sibling relationships is largely not documented. Until the time that we have research on these issues, we turn to the literature on the impact of genetic information and illness on siblings and present existing data, largely based on conditions arising from single gene disorders.


Cystic Fibrosis Stem Cell Transplant Human Leukocyte Antigen Graft Versus Host Disease Family Communication 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was developed with support from the New England Genetics Collaborative, funded by a federal cooperative agreement from the United States Department of Health and Human Services, Health Resources and Services Administration, CFDA #93.110, U22MC10980 (to J.F.), and by the Intramural Research Program of the National Institutes of Health, National Cancer Institute, Pediatric Oncology Branch (to L.W. and T.B.). Angie Boyce was helpful in manuscript preparation.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Joanna Fanos
    • 1
  • Lori Wiener
    • 2
  • Tara Brennan
    • 3
  1. 1.Dartmouth Medical SchoolLebanonUSA
  2. 2.National lnstitutes of HealthBethesdaUSA
  3. 3.Children’s National Medical CenterWashingtonUSA

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