Commercial Applicability of Cell Microancapsulation: A Review of Intellectual Property Rights

  • Stephan M. Meier
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 670)


Maturity and applicability of a distinct field of science can be estimated, using a review of current filing statistics of patent applications. Therefore, hereby a search based on international classifications has been directed to the world intellectual property organization (WIPO) to determine the amount and content of patent applications related to the field of cell microencapsulation. The search was evaluated with regard to the distinct indications envisaged and an evaluation of possible technology gaps for fostering further progress was conducted.


Intellectual Property Patent Application International Patent World Intellectual Property Organization Patent Literature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Orive G, Hernandez RM, Gascon AR et al. Cell encapsulation: promise and progress. Nat Med 2003; 9(1):104–107.CrossRefPubMedGoogle Scholar
  2. 2.
    Orive G, Hernandez RM, Rodriguez GA et al. History, challenges and perspectives of cell microencapsulation. Trends Biotechnol 2004; 22(2):87–92.CrossRefPubMedGoogle Scholar
  3. 3.
    Wo/1989/004655, In vivo delivery of neurotransmitters by implanted, encapsulated cells.Google Scholar
  4. 4.
    WO/1990/012603, neomorphogenesis of cartilage in vivo from cell culture.Google Scholar
  5. 5.
    WO/1990/012604, method for implanting large volumes of cells on polymeric matrices.Google Scholar
  6. 6.
    WO/1992/007525, close vascularization implant material.Google Scholar
  7. 7.
    WO/1993/008766, Transplant protective coating.Google Scholar
  8. 8.
    WO/1993/008850, Prevascularized polymeric implants for organ transplantation.Google Scholar
  9. 9.
    WO/1993/019700, Systems and methods for cells implants.Google Scholar
  10. 10.
    WO/1993/019701, Angiogenic tissue implant systems and methods.Google Scholar
  11. 11.
    WO/1993/022427, Method of culturing viable cells and method of regulating the level of a compound in a body fluid.Google Scholar
  12. 12.
    WO/1994/009722, Method and device for reconstruction of articular cartilage.Google Scholar
  13. 13.
    WO/1994/018307, Cell induction device.Google Scholar
  14. 14.
    WO/1994/020151, Process for producing an implant from cell cultures.Google Scholar
  15. 15.
    WO/1995/001810, Implantable prosthesis, kit and device for manufacturing the same.Google Scholar
  16. 16.
    WO/1995/003011, Bone regeneration templates.Google Scholar
  17. 17.
    WO/1995/011007, Preparation of medical devices by solid freeform fabrication methods.Google Scholar
  18. 18.
    WO/1995/018583, Ported tissue implant systems and methods of using same.Google Scholar
  19. 19.
    WO/1995/018584, Method for implanting tissue in a host.Google Scholar
  20. 20.
    WO/1995/033421, Biomatrix for tissue regeneration.Google Scholar
  21. 21.
    WO/1996/032076, Tissue implant systems.Google Scholar
  22. 22.
    WO/1996/036296, Multiple layer, formed-in-place immunoisolation membrane structures for implantation of cells in host tissue.Google Scholar
  23. 23.
    WO/1996/036562, Bone substitution material and a method of its manufacture.Google Scholar
  24. 24.
    WO/1996/039100, Tissue loading system for implantable biological devices.Google Scholar
  25. 25.
    WO/1996/039992, Apparatus and method for sterilizing, seeding, culturing, storing, shipping, and testing replacement cartilage tissue constructs.Google Scholar
  26. 26.
    WO/1996/040002, Vascularized tissue regeneration matrices formed by solid free-form fabrication methods.Google Scholar
  27. 27.
    WO/1997/013474, Retrievable bioartificial implants.Google Scholar
  28. 28.
    WO/1997/015243, Induction of immunological tolerance.Google Scholar
  29. 29.
    WO/1997/025936, Buffered resorbable internal fixation devices for repair of bone fractures.Google Scholar
  30. 30.
    WO/1997/030662, Method for making and/or repairing cartilage.Google Scholar
  31. 31.
    WO/1997/030778, Novel artificial pancreas.Google Scholar
  32. 32.
    WO/1997/044070, Polysaccharide sponges for cell culture and transplantation.Google Scholar
  33. 33.
    Wo/1997/045532, hyaluronan based biodegradable scaffolds for tissue repair.Google Scholar
  34. 34.
    Wo/1998/002113, implant assembly.Google Scholar
  35. 35.
    Wo/1998/005274, compositions and methods for intervertebral disc reformation.Google Scholar
  36. 36.
    Wo/1998/016209, bioceramic compositions.Google Scholar
  37. 37.
    Wo/1998/051236, artificial gut.Google Scholar
  38. 38.
    Wo/1999/039724, treatment of bony defects with osteoblast precursor cells.Google Scholar
  39. 39.
    Wo/1999/048541, assembled scaffolds for three-dimensional cell culturing and tissue generation.Google Scholar
  40. 40.
    Wo/1999/055252, guided development and support of hydrogel-cell compositions.Google Scholar
  41. 41.
    Wo/2000/009043, osteoinduction of cortical bone allografts by coating with biopolymers seeded with recipient periosteal bone cells.Google Scholar
  42. 42.
    Wo/2000/009179, methods, instruments and materials for chondrocyte cell transplantation.Google Scholar
  43. 43.
    Wo/2000/012028, implantable system with drug-eluting cells for on-demand local drug delivery.Google Scholar
  44. 44.
    Wo/2000/013615, implant, method of making the same and use of the same.Google Scholar
  45. 45.
    Wo/2000/050049, artificial salivary gland.Google Scholar
  46. 46.
    Wo/2001/006949, in vitro repair of bone and/or cartilage defects.Google Scholar
  47. 47.
    Wo/2001/008610, kit for chondrocyte cell transplantation.Google Scholar
  48. 48.
    Wo/2001/017463, improved resorbable scaffolds to promote cartilage regeneration.Google Scholar
  49. 49.
    Wo/2001/082828, tissue engineered testicular prosthesis and use thereof.Google Scholar
  50. 50.
    Wo/2001/083709, isolation of mesenchymal stem cells and use thereof.Google Scholar
  51. 51.
    Wo/2001/085900, a device for cell implantation.Google Scholar
  52. 52.
    Wo/2001/087192, tissue engineered stents.Google Scholar
  53. 53.
    Wo/2002/053193, tissue engineering of three-dimensional vascularized using microfabricated polymer assembly technology.Google Scholar
  54. 54.
    Wo/2002/076344, delivery of drugs from sustained release devices implanted in myocardial tissue or in the pericardial space.Google Scholar
  55. 55.
    Wo/2002/088331, tridimensional biocompatible support structure for bioartificial organs and uses thereof.Google Scholar
  56. 56.
    Wo/2002/091955, artificial kidney having function of metabolizing protein and mehtod of constructing the same.Google Scholar
  57. 57.
    Wo/2003/075800, improved bone-tendon-bone assembly with cancellous allograft bone block.Google Scholar
  58. 58.
    Wo/2003/094703, tissue engineered osteochondral implant.Google Scholar
  59. 59.
    Wo/2004/022000, antibiotic microspheres for treatment of infections and osteomyelitis.Google Scholar
  60. 60.
    Wo/2004/084703, temporary embolization using inverse thermosensitive polymers.Google Scholar
  61. 61.
    Wo/2004/093934, materials and methods for augmenting and/or repairing intervertebral discs.Google Scholar
  62. 62.
    Wo/2004/096983, novel glue for cartilage repair.Google Scholar
  63. 63.
    Wo/2005/000169, prosthetic device for cartilage repair.Google Scholar
  64. 64.
    Wo/2005/009356, method for the preparation of controlled release formulations.Google Scholar
  65. 65.
    Wo/2005/038016, cartilage replacement implant and method for producing a cartilage replacement implant.Google Scholar
  66. 66.
    Wo/2005/046445, artificial tissue systems and uses thereof.Google Scholar
  67. 67.
    Wo/2005/046748, device and method for attracting diseased cells and foreign substances.Google Scholar
  68. 68.
    Wo/2006/038211, disease treatment via developing non-syngeneic graft transplantation.Google Scholar
  69. 69.
    Wo/2006/066327, an implantable biomaterial and a method of producing same.Google Scholar
  70. 70.
    Wo/2006/069349, cell-loaded prostheses for regenerative intraluminal applications.Google Scholar
  71. 71.
    Wo/2007/084068, pharmaceutical formulations comprising dextran with molecular weight of 1.0-100kda and processes for their preparation.Google Scholar
  72. 72.
    Wo/2007/115336, a shape-based approach for scaffoldless tissue engineering.Google Scholar
  73. 73.
    Wo/2007/125323, implant for tissue engineering.Google Scholar
  74. 74.
    Wo/2008/004260, bio-membrane for tissue regeneration.Google Scholar
  75. 75.
    Wo/1991/010425, cell capsule extrusion systems.Google Scholar
  76. 76.
    Wo/1993/000063, capsule extrusion systems.Google Scholar
  77. 77.
    Wo/1995/033553, polymeric microbeads and method of preparation.Google Scholar

Copyright information

© Landes Bioscience and Springer Science+Business Media 2010

Authors and Affiliations

  • Stephan M. Meier
    • 1
  1. 1.DüsseldorfGermany

Personalised recommendations