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Inorganic Nanoporous Membranes for Immunoisolated Cell-Based Drug Delivery

  • Adam Mendelsohn
  • Tejal Desai
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 670)

Abstract

Materials advances enabled by nanotechnology have brought about promising approaches to improve the encapsulation mechanism for immunoisolated cell-based drug delivery. Cell-based drug delivery is a promising treatment for many diseases but has thus far achieved only limited clinical success. Treatment of insulin dependent diabetes mellitus (IDDM) by transplantation of pancreatic β-cells represents the most anticipated application of cell-based drug delivery technology. This review outlines the challenges involved with maintaining transplanted cell viability and discusses how inorganic nanoporous membranes may be useful in achieving clinical success.

Keywords

Islet Transplantation Silicon Membrane Alumina Membrane Titanium Foil Nanoporous Alumina 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Landes Bioscience and Springer Science+Business Media. 2010

Authors and Affiliations

  • Adam Mendelsohn
    • 1
  • Tejal Desai
    • 1
  1. 1.UCSF/UCB Joint Graduate Group in BioengineeringUniversity of California, San Francisco, University of CaliforniaBerkeleyUSA

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