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New Frontiers in Respiratory Control pp 33–36Cite as

Anatomical Changes of Phrenic Motoneurons During Development

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 669))

Abstract

Although the phrenic motoneurons are relatively well-developed at the time of birth as compared to non-respiratory motoneurons, they show distinct anatomical changes during postnatal development. In the present review we summarize anatomical changes of phrenic motoneurons during pre- and postnatal development. Cell bodies of phrenic motoneurons migrate into the ventromedial region of the ventral horn of C3-C6 by E13-E14 in the rat. During development the sizes and surface areas of phrenic motoneurons are increased with changes in dendritic morphology.

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Author information

Authors and Affiliations

  1. Department of Medicine, Keio University Tsukigase Rehabilitation Center, Shizuoka, Japan

    Yasumasa Okada

  2. Department of Anatomy and Morphological Neuroscience, Shimane University School of Medicine, Izumo, Japan

    Shigefumi Yokota & Yukihiko Yasui

  3. Department of Orthopaedic Surgery, Hino Municipal Hospital, Tokyo, Japan

    Yoshio Shinozaki

  4. Graduate School of Engineering, Chiba University, Chiba, Japan

    Fumikazu Miwakeichi

  5. Department of Physiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

    Yoshitaka Oku

Authors
  1. Yasumasa Okada
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  2. Shigefumi Yokota
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  3. Yoshio Shinozaki
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  4. Fumikazu Miwakeichi
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  5. Yoshitaka Oku
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  6. Yukihiko Yasui
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Corresponding author

Correspondence to Yasumasa Okada .

Editor information

Editors and Affiliations

  1. Showa University School of Medicine, Hatanodai, Shinagawa-ku 1-5-8-5-8, Tokyo, 142-8555, Japan

    Ikuo Homma

  2. Showa University School of Medicine, Hatanodai, Shinagawa-ku 1-5-8-5-8, Tokyo, 142-8555, Japan

    Hiroshi Onimaru

  3. Jyuntendo University School of Medicine, Hongo, Bunkyo-ku 2-1-1-1-1, Tokyo, 113-8421, Japan

    Yoshinosuke Fukuchi

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Okada, Y., Yokota, S., Shinozaki, Y., Miwakeichi, F., Oku, Y., Yasui, Y. (2010). Anatomical Changes of Phrenic Motoneurons During Development. In: Homma, I., Onimaru, H., Fukuchi, Y. (eds) New Frontiers in Respiratory Control. Advances in Experimental Medicine and Biology, vol 669. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5692-7_7

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