Influence of Cycling History on the Ventilatory Response to Cycle-Ergometry in Humans: A Role for Respiratory Memory?

  • Andrew J. Cathcart
  • Brian J. Whipp
  • Anthony P. Turner
  • John Wilson
  • Susan A. Ward
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 669)


The ventilatory (V' E) mechanisms subserving stability of alveolar and arterial PCO2 (PACO2, PaCO2) during moderate exercise (< lactate threshold, θL) remain controversial. As long-term modulation has been argued to be an important contributor to this control process, we proposed that subjects with no experience of cycling (NEx) might provide insight into this issue. With no exercise familiarization, 9 sedentary NEx subjects and 9 age-, sex-, and activity-matched controls (C) who had cycled regularly for recreational purposes since childhood completed a square-wave (6-min stage) cycle-ergometry test: 10 W-WR1-WR2-WR1-10 W; WR1 range 25–45 W, WR2 range 50–90 W. WRs were subsequently confirmed to <θL. The NEx V'E-V'CO2 slope, V'E–intercept, mean PACO2 and estimated alveolar ventilation were not different from C. In conclusion, these findings provide no support for, and possibly support for no, V'E control during moderate exercise being modulated by influences related to long-term exercise history.


Moderate Exercise Alveolar Ventilation Recreational Purpose Pedalling Rate Associative Conditioning 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Andrew J. Cathcart
    • 1
  • Brian J. Whipp
    • 2
  • Anthony P. Turner
    • 3
  • John Wilson
    • 4
  • Susan A. Ward
    • 5
  1. 1.Centre for Exercise Science and MedicineUniversity of GlasgowGlasgowUK
  2. 2.Human Bio-Energetics Research CentreCrickhowellUK
  3. 3.Department of Physical EducationUniversity of EdinburghEdinburghUK
  4. 4.Centre for Exercise Science and MedicineUniversity of GlasgowGlasgowUK
  5. 5.Human Bio-Energetics Research Centre, Centre for Exercise Science and MedicineCrickhowell and University of GlasgowCrickhowellUK

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