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Influence of Cycling History on the Ventilatory Response to Cycle-Ergometry in Humans: A Role for Respiratory Memory?

  • Andrew J. Cathcart
  • Brian J. Whipp
  • Anthony P. Turner
  • John Wilson
  • Susan A. Ward
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 669)

Abstract

The ventilatory (V' E) mechanisms subserving stability of alveolar and arterial PCO2 (PACO2, PaCO2) during moderate exercise (< lactate threshold, θL) remain controversial. As long-term modulation has been argued to be an important contributor to this control process, we proposed that subjects with no experience of cycling (NEx) might provide insight into this issue. With no exercise familiarization, 9 sedentary NEx subjects and 9 age-, sex-, and activity-matched controls (C) who had cycled regularly for recreational purposes since childhood completed a square-wave (6-min stage) cycle-ergometry test: 10 W-WR1-WR2-WR1-10 W; WR1 range 25–45 W, WR2 range 50–90 W. WRs were subsequently confirmed to <θL. The NEx V'E-V'CO2 slope, V'E–intercept, mean PACO2 and estimated alveolar ventilation were not different from C. In conclusion, these findings provide no support for, and possibly support for no, V'E control during moderate exercise being modulated by influences related to long-term exercise history.

Keywords

Moderate Exercise Alveolar Ventilation Recreational Purpose Pedalling Rate Associative Conditioning 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Cathcart, A., Herrold, N., Turner, A.P., Wilson, J., and Ward, S.A. (2005) Absence of long-term modulation in response to external dead-space loading during moderate exercise in humans. Europ. J. Appl. Physiol. 93, 411–420.CrossRefGoogle Scholar
  2. DuBois, A.B., Britt, A.G., and Fenn, W.O. (1952) Alveolar CO2 during the respiratory cycle. J. Appl. Physiol. 4, 535–548.PubMedGoogle Scholar
  3. Helbling, D., Boutellier, U., and Spengler, C.M. (1997) Modulation of the ventilatory increase at the onset of exercise in humans. Respir. Physiol. 109, 219–229.CrossRefPubMedGoogle Scholar
  4. Kaufman, M.P. and Forster, H.V. (1996) Reflexes controlling circulatory, ventilatory and airway responses to exercise. In L.B. Rowell and J.T. Shepherd (Eds.), Handbook of physiology, Section 12: Exercise: Regulation and integration of multiple systems (pp. 381–447). New York: Oxford University Press.Google Scholar
  5. Martin, P.A. and Mitchell, G.S. (1993) Long term modulation of the exercise ventilatory response in goats. J. Physiol. 470, 601–617.PubMedGoogle Scholar
  6. Moosavi, S.H., Guz, A., and Adams, L. (2002) Repeated exercise paired with “imperceptible” dead space loading not alter V'E of subsequent exercise in humans. J. Appl. Physiol. 92, 1159–1168.PubMedGoogle Scholar
  7. Somjen, G.G. (1992) The missing error signal – regulation beyond negative feedback. N.I.P.S. 7, 184–185.Google Scholar
  8. Turner, D.L. and Sumners, D.P. (2002) Associative conditioning of the exercise ventilatory response in humans. Respir. Physiol. Neurobiol. 132, 159–168.CrossRefGoogle Scholar
  9. Whipp, B.J., Lamarra, N., Ward, S.A., Davis, J.A., and Wasserman, K. (1990) Estimating arterial PCO2 from flow-weighted and time-averaged alveolar PCO2 during exercise. In G.D. Swanson and F.S. Grodins (Eds.), Respiratory control: A modelling perspective (pp. 91–99). New York: Plenum.Google Scholar
  10. Whipp, B.J. and Ward, S.A. (1991) The coupling of ventilation to pulmonary gas exchange during exercise. In B.J. Whipp and K. Wasserman (Eds.), Pulmonary physiology and pathophysiology of exercise (pp. 271–307). New York: Dekker.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Andrew J. Cathcart
    • 1
  • Brian J. Whipp
    • 2
  • Anthony P. Turner
    • 3
  • John Wilson
    • 4
  • Susan A. Ward
    • 5
  1. 1.Centre for Exercise Science and MedicineUniversity of GlasgowGlasgowUK
  2. 2.Human Bio-Energetics Research CentreCrickhowellUK
  3. 3.Department of Physical EducationUniversity of EdinburghEdinburghUK
  4. 4.Centre for Exercise Science and MedicineUniversity of GlasgowGlasgowUK
  5. 5.Human Bio-Energetics Research Centre, Centre for Exercise Science and MedicineCrickhowell and University of GlasgowCrickhowellUK

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