Abstract
Patients with a prolonged intensive care unit (ICU) stay represent 5.6 % of ICU admissions and 39.7 % of ICU bed-days [1]. Based on these incidence rates, it would be useful to identify risk factors associated with prolonged ICU and hospital stays to help guide the delivery of ICU care. Cytomegalovirus (CMV) infection could be one of the markers for this subgroup of more critically ill patients. CMV is well recognized as an important pathogen in patients with acquired immunodeficiency syndrome (AIDS) [2], and in solid organ [3] and hematopoetic stem-cell [4] transplant recipients. The direct (end-organ disease) and the indirect (allograft rejection, atherosclerosis, CMV-induced immunosuppression with increased risk of post-transplant lymphoprolipherative disorders and secondary bacterial and fungal infections) effects of CMV infection are well described in immunocompromised hosts [3, 5, 6].
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Florescu, D.F., Kalil, A.C. (2010). Cytomegalovirus Infections in Non-immunocompromised Critically III Patients. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5562-3_21
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DOI: https://doi.org/10.1007/978-1-4419-5562-3_21
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-5561-6
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