Testicular Catch-Up Growth
Testicular growth depends on many different factors; through embryology, clinical data, and experimental studies we present the development of testes and the correlation with volume loss due to different diseases. We then show how the most common pediatric pathologies may affect testicular size and fertility potential. An undescended testis may affect spermatogenesis and the testicular volume, and this finding is strictly correlated with the timing of surgery. Varicocele still remains the most common surgical correctable andrological disease in adolescents and adults. Varicocele is associated with testicular growth arrest, impaired fertility, and low quality of spermatogenesis. Varicocelectomy, as suggested by international committees, should be performed at any age. Testicular catch-up growth after orchidopexy and varicocelectomy is common and still remains the most important outcome.
KeywordsAndrogen Receptor Sertoli Cell Leydig Cell Undescended Testis Testicular Volume
The author thanks the Pediatric Surgical Unit, Department of Surgical Science, University of Verona, for the assistance in collecting data and bibliography.