Anthropometric Measurements, Adipokines and Abdominal Aortic Calcification

  • Adam Franklin Parr
  • Jonathan Golledge


Obesity and arterial calcification are associated with increased cardiovascular morbidity and mortality. The relationship between obesity and abdominal aortic calcification has been under investigated. The majority of research has focused on the relationship between clinical anthropometric measures and aortic calcification, with mixed results. Numerous calcification measurement protocols have hindered appropriate analysis of the literature. However, recently a reproducible computed tomography method for aortic calcification quantification has been published. Similarly, many methods are available for anthropometric assessment. Clinical measures include body mass index, waist circumference, waist to hip ratio, skin fold and percent body fat. Alternatively, computed tomography can be reproducibly utilized to measure abdominal adipose diameters, area and volume. Recently, the relationship between calcification and anthropometric measurements has been investigated by computed tomography. It was found that a measure of visceral adiposity was associated with abdominal aortic calcification. In addition, visceral adiposity was positively and negatively correlated to circulating concentrations of osteoprotegerin and leptin, respectively. This has provided a possible pathogenic mechanism for the accumulation of abdominal aortic calcification. The aims of this chapter are two fold: 1. To outline the various anthropometric and calcification protocols currently employed for vascular research. 2. To review the current literature regarding the relationship between anthropometric measures and abdominal aortic calcification.


Coronary Artery Calcification Abdominal Aortic Aneurysm Abdominal Aortic Aneurysm Vascular Calcification Hounsfield Unit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Abdominal Aortic Aneurysm


Anterior-posterior diameter – skin to skin


Anterior-posterior diameter – muscle to muscle


Anterior-posterior ratio (AP2/AP1)


Body mass index


Computed tomography


Center hounsfield unit


External beam computed tomography


Hounsfield unit


International diabetes federation


Subcutaneous fat


Transverse diameter – skin to skin


Transverse diameter – muscle to muscle


Transverse ratio




Window width hounsfield unit


Waist hip ratio


World Health Organisation



We would like to thank Ms Moira McCann, Ms Barbara Bradshaw, Mr Keith Rich and The Townsville Hospital radiology and vascular surgery departments.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.The Vascular Biology UnitJames Cook UniversityTownsvilleAustralia

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