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Host Gene Polymorphisms and Disease/Treatment Outcomes in HIV and Viral Coinfections

  • Jacob K. Nattermann
  • Jürgen K. Rockstroh
Chapter

Abstract

Since the early days of the current HIV type 1 (HIV-1) pandemic, it has been observed that both susceptibility to HIV-1 infection and natural course of disease are highly variable. These differences are the result of multifaceted interactions between virus, host, and environment, and these interactions may be even more complex in the case of coinfection with other viruses such as HBV or HCV. With respect to the host, it is known that genetic differences importantly contribute to this variation.

Keywords

Human Leukocyte Antigen Sustain Virologic Response Human Leukocyte Antigen Class Human Immune Deficiency Virus Human Leukocyte Antigen Allele 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of Internal Medicine IUniversity of BonnBonnGermany
  2. 2.Department of Internal Medicine IUniversity of BonnBonnGermany

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