Epidemiology of Liver Disease in Human Immunodeficiency Virus-Infected Persons

Chapter

Abstract

In the era of combination antiretroviral therapy (CART) and improved survival [1], liver disease has become a leading cause of morbidity and mortality among HIV-infected persons [2–4]. The term “liver disease” encompasses a wide spectrum, ranging from asymptomatic mild elevations of liver enzymes (aspartate aminotransferase, AST; alanine aminotransferase, ALT; alkaline phosphatase, ALP) to cirrhosis and end stage liver disease with all its complications (e.g., ascites, esophageal varices, hepatic encephalopathy).

Keywords

Toxicity Hepatitis Attenuation Tuberculosis Interferon 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.School of Medicine/Division of Infectious DiseasesUniversity of PittsburghPittsburgUSA

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