Head and Neck Neuroendocrine Tumors

  • Edward B. Stelow
Part of the Molecular Pathology Library book series (MPLB, volume 3)


The head and neck region contains a number of disparate organs ranging from skin to brain, and many of the neuroendocrine tumors of these organs have been discussed elsewhere in this book (skin, thyroid, and pituitary gland). Extra-adrenal paragangliomas, although also discussed elsewhere, will be mentioned and discussed briefly as they pertain to the ear and upper aerodigestive tract. This chapter will concentrate on neuroendocrine tumors of the ear, upper aerodigestive tract, and salivary glands. Focusing on these entities leaves only a few head- and neck-specific tumors to discuss, including middle ear adenoma, neuroendocrine carcinomas of the upper aerodigestive tract and salivary glands, uncommon and unique neuroectodermal tumors of the area, and, as mentioned, paraganglioma. Even if taken together, these tumors are exceedingly rare and little is known regarding the genetics of the tumors. While this limits our discussion, it does leave open some exciting avenues of possible research.


Carcinoid Tumor Small Cell Carcinoma Pleomorphic Adenoma Neuroendocrine Carcinoma Merkel Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Edward B. Stelow
    • 1
  1. 1.Department of PathologyUniversity of VirginiaCharlottesvilleUSA

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