Kidney Allocation: Role of UNOS and OPOs

  • Patricia L. Adams
  • Walter K. Graham
  • Susan Gunderson
Chapter

Abstract

The UNOS is a not-for-profit, private, voluntary membership organization incorporated in the Commonwealth of Virginia, which qualifies as a tax exempt charity under IRC section 501(c)(3). Since 1986, it has been the sole holder of a contract from the federal government to operate the national OPTN. Its story is one of the many remarkable successes in organ transplantation.

Keywords

Ischemia Transportation 

Notes

Glossary

AATB

American Association of Tissue Banks

AOPO

Association of Organ Procurement Organizations

CMS

Center for Medicare and Medicaid Services; one branch of HHS

CPRA

calculated panel reactive antibody; measures a recipient’s preformed antibodies to donor antigens

Crossmatch

a histocompatibility test measuring the degree to which a recipient’s immune system reacts against a donor

DCD

donation after cardiac death

DonorNet®

electronic donor information and organ offer system

Donor swaps

when two or more recipients exchange living donors because their original donors cannot donate to them because of incompatible blood type or positive crossmatch

DOT

Department of Transplantation

DSA

designated service area

ECD

expanded criteria donor

FDA

Federal Drug Administration

HCFA

Health Care Financing Administration; former name for CMS

HHS

Department of Health and Human Services

HRSA

Health Resources and Services Administration; one branch of HHS; home of the DOT

IHI

Institute for Healthcare Improvement

KAS

kidney allocation system

LYFT

life years from transplant

MPSC

Membership and Professional Standards Committee

NEOB

New England Organ Bank

NOTA

National Organ and Transplant Act of 1984

OPO

organ procurement organization

OPTN

Organ Procurement and Transplant Network

Organ donation conversion rate

number of actual donors as percent of eligible donors

RRT

renal replacement therapy

SCD

standard criteria donor

Sensitized candidate

has preformed anti-HLA antibodies (PRA) in the blood

SEROPP

South-Eastern Regional Organ Procurement Program

SEOPF

South-Eastern Organ Procurement Foundation

SRTR

Scientific Registry for Transplant Recipients

SSA

Social Security Act

Transplant center

usually a large hospital complex where multiple types of transplants done

Transplant program

usually part of a transplant center; focused on one organ

Unet®

the electronic matching system

UNOS

United Network for Organ Sharing

0-ABDR MM

zero mismatch; this refers to the situation when the donor has no allele which is different from the recipient even though the donor does not have all the alleles of the recipient

References

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Copyright information

© Springer-Verlag US 2010

Authors and Affiliations

  • Patricia L. Adams
    • 1
  • Walter K. Graham
    • 2
  • Susan Gunderson
    • 3
  1. 1.Section on Nephrology, WFU School of MedicineWake Forest University BaptistMedical Center, Medical Center Boulevard, NC Baptist HospitalWinston-SalemUSA
  2. 2.United Network for Organ SharingRichmondUSA
  3. 3.LifeSourceSt. PaulUSA

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