Temporomandibular Disorders and its Relationship with Fibromyalgia

  • Ana Mirian VellyEmail author
  • Hong Chen
  • João R. Ferreira
  • James R. Fricton


Temporomandibular Disorder (TMD) is the second most common musculoskeletal condition resulting in orofacial pain and disability. Although most cases of Temporomandibular Muscle and Joint Disorders (TMJD) are mild and self-limiting, about 10% of TMJD patients develop severe disorders associated with chronic pain and disability. One in two patients seeking care still has pain 5 years later. The treatment of TMD has been an increasing financial burden, with annual U.S. costs doubling in the last decade to $4 billion annually. It has been found that fibromyalgia (FMS) plays a significant role in the persistence of TMD. This chapter reviews the characteristics and the relationship between TMD and FMS, highlighting the importance of this comorbid condition for the management of TMD.


Chronic Fatigue Syndrome Muscle Fiber Type Mechanical Hyperalgesia Pressure Pain Threshold Widespread Pain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



American College of Rheumatology diagnostic criteria


Acid-sensing ion channels


Brain-derived neurotrophic factor






Myofascial pain




Nerve growth factor




Research Diagnostic Criteria


Tender points


Temporomandibular Disorder


Trigger points


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Copyright information

© Springer Science+Business Media, LLC 2013

Authors and Affiliations

  • Ana Mirian Velly
    • 1
    • 2
    Email author
  • Hong Chen
    • 3
  • João R. Ferreira
    • 4
  • James R. Fricton
    • 5
  1. 1.Department of Dentistry, Centre for Clinical Epidemiology and Community StudiesJewish General HospitalMontréalCanada
  2. 2.Department of Diagnostic and Biological Sciences, Division of TMD and Orofacial PainUniversity of MinnesotaMinneapolisUSA
  3. 3.Center for Neurosensory Disorders, Orofacial Pain ClinicUniversity of North Carolina - Chapel Hill, School of DentistryChapel HillUSA
  4. 4.NC Oral Health InstituteUniversity of North Carolina, School of DentistryChapel HillUSA
  5. 5.University of MinnesotaMinneapolisUSA

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