Hyperkeratotic or crusted scabies, formerly called Norwegian scabies, is caused by the same mite, Sarcoptes scabiei, as common scabies.1 When it was first described by Danielssen and Boeck in 1848 in Norwegian lepers, it was not appreciated as a manifestation of immunodeficiency. Norwegian scabies was seen in those with Down’s syndrome (trisomy 21) or severe mental retardation. It is increasingly being seen in immunocompromised patients of varying types including those with human immunodeficiency virus (HIV) disease, acquired immune deficiency syndrome (AIDS), human T-lymphotropic virus-1 (HTLV-1) associated adult T-cell leukemia/lymphoma,2 chronic lymphocytic leukemia, organ transplantation, patients on treatment with immunosuppressants or systemic steroids, physical debilitation (critical illness, kwashiorkor), and neurological disorders with decreased cutaneous sensation and reduced ability to mechanically remove the mites and destroy the burrows by scratching (tabes dorsalis, syringomyelia, and Parkinson’s disease).
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Hengge U, Currie BJ, Jäger G, Lupi O, Schwartz RA. Scabies: a ubiquitous neglected skin disease. Lancet Infect Dis. 2006;6:769–79.PubMedCrossRefGoogle Scholar
del Giudice P, Sainte Marie D, Gérard Y, Couppié P, Pradinaud R. Is crusted (Norwegian) scabies a marker of adult T cell leukemia/lymphoma in human T lymphotropic virus type I-seropositive patients? J Infect Dis. 1997;176(4):1090–2.PubMedCrossRefGoogle Scholar
Binić I, Janković A, Janković D, Ljubenovic M. Crusted (Norwegian) scabies following systemic and topical corticosteroid therapy. J Korean Med Sci. 2010;25(1):188–91.PubMedCrossRefGoogle Scholar
Fajardo-Velázquez R, Urdez-Hernández E, Ysita-Morales A. Nosocomial outbreak of scabies from a Norwegian scabies case. Salud Publica Mex. 2004;46(3):251–4.PubMedCrossRefGoogle Scholar
Glover R, Young L, Goltz RW. Norwegian scabies in acquired immunodeficiency syndrome: report of a case resulting in death from associated sepis. J Am Acad Dermatol. 1987;16:396–9.PubMedCrossRefGoogle Scholar
Hulbert TV, Larsen RA. Hyperkeratotic (Norwegian) scabies with gram-negative bacterium as the initial presentation of AIDS. Clin Infect Dis. 1992;14:1164–5.PubMedCrossRefGoogle Scholar
Bonomo RA, Jacobs M, Jacobs G, Graham R, Salata RA. Norwegian scabies and a toxic shock syndrome toxin 1-producing strain of Staphylococcus aureus endocarditis in a patient with trisomy 21. Clin Infect Dis. 1998;27:645–6.PubMedCrossRefGoogle Scholar