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Reproductive Endocrinology and Infertility pp 509–516Cite as

Sperm Banking, Donation, and Transport in the Age of Assisted Reproduction: Federal and State Regulation

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Abstract

Cryopreservation of semen is a common procedure, both for autologous sperm banking and for donor sperm insemination. Additionally, new techniques employing semen banking are now common, including the use of epididymal aspirates and testicular biopsy specimens used for assisted reproductive therapies (ART). This chapter explores the regulatory, scientific, and practical aspects of sperm cryopreservation and banking.

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References

  1. Centers for Disease Control (1988) Semen Banking, organ and tissue transplantation and HIV antibody testing. In: Morbidity and Mortality Weekly Report 37:58-59

    Google Scholar 

  2. Meirow D, Schenker JG (1993) Sperm donation - should the use of frozen-thawed semen alter treatment modalities? Int J Fertil 38:325-331

    Google Scholar 

  3. Merino G, Murrieta S, Rodriguez L, Sandoval C (1994) Semen cryopreservation/artificial insemination. Mol Androl 6:170-175

    Google Scholar 

  4. Ginsburg KA, Montgomery-Rice V (1996) Therapeutic donor insemination: screening, indications and technique. In: Centola GM, Ginsburg KA (eds) Evaluation and treatment of the infertile male. Cambridge University Press, Cambridge, pp 171-193

    Chapter  Google Scholar 

  5. Bunge RG, Sherman JK (1953) Fertilizing capacity of frozen human spermatozoa. Nature 172:767

    Article  CAS  PubMed  Google Scholar 

  6. Sherman JK (1973) Synopsis fo the use of frozen semen since 1964: State of the art of human semen banking. Fertil Steril 24:397-412

    CAS  PubMed  Google Scholar 

  7. Clarke GN, Liu deY, Baker HW (2006) Recovery of human sperm motility and ability to interact with the human zona pellucida after more than 28 years of storage in liquid nitrogen. Fertil Steril 86:721-722

    Article  PubMed  Google Scholar 

  8. Schover LR, Brey K, Lichtin A, Lipshultz LI, Jeha S (2002) Oncologists’ attitudes and practices regarding banking sperm before cancer treatment. J Clin Oncol 20:1890-1897

    Article  PubMed  Google Scholar 

  9. Anger JT, Gilbert BR, Goldstein M (2003) Cryopresrvation of sperm: indications, methods and results. J Urol 170:1079-1084

    Article  PubMed  Google Scholar 

  10. Ben Rhouma K, Marrakchi H, Khouja H, Attalah K, Ben Miled E, Sakly M (2003) Outcome of intracytoplasmic injection of fresh and frozen-thawed testicular spermatozoa. A comparative study. J Reprod Med 48:349-354

    PubMed  Google Scholar 

  11. Boyle KE, Thomas AJ, Marmar JL, Hirschberg S, Belker AM, Jarow JP (2006) Sperm harvesting and cryopreservation during vasectomy reversal is not cost effective. Fertil Steril 85:961-964

    Article  PubMed  Google Scholar 

  12. Hallak J, Sharma RK, Wellstead C, Agarwal A (2000) Cryopreservation of human spermatozoa: comparison of TEST-yolk buffer and glycerol. Int J Fertil Women’s Med 45:38-42

    CAS  Google Scholar 

  13. Ragni G, Somigliana E, Restelli L, Salvi R, Arnoldi M, Paffoni A (2003) Sperm banking and rate of assisted reproduction treatment: insights from a 15-year cryopreservation program for male cancer patients. Cancer 97:1624-1629

    Article  PubMed  Google Scholar 

  14. Agarwal A, Tolentino MV Jr, Sidhu RS, Avzman I, Lee JC, Thomas AJ Jr, Shekarriz M (1995) Effect of cryopreservation on semen quality in patients with testicular cancer. Urology 46:382-389

    Article  CAS  PubMed  Google Scholar 

  15. Agarwal A (2000) Semen banking in patients with cancer: 20 year experience. Int J Androl 23:16-19

    Article  PubMed  Google Scholar 

  16. Chung K, Irani J, Knee G, Efymow B, Blasco L, Patrizio P (2004) Sperm cryopreservation for male patients with cancer: an epidemiological analysis at the University of Pennsylvania. Eur J Obstet Gynecol Reprod Biol 113:S7-S11

    Article  PubMed  Google Scholar 

  17. Walschaerts M, Muller A, Daudin M, Hennebicq S, Eric H, Thonneau P (2007) Sperm cryopreservation: Recent and marked increase in use for testicular cancer compared with hodgkin disease. J Androl 28:801-803

    Article  PubMed  Google Scholar 

  18. Donnelly ET, Steele EK, McClure N, Lewis SEM (2001) Assessment of DNA integrity and morphology of ejaculated sperm from fertile and infertile men before and after cryopreservation. Hum Reprod 16:1191-1199

    Article  CAS  PubMed  Google Scholar 

  19. Thepot F, Mayaux MJ, Czyglick F, Wack T, Selva J, Jalbert P (1996) Incidence of birth defects after artificial insemination with frozen donor spermatozoa: a collaborative study of the French CECOS federation on 11535 pregnancies. Hum Reprod 11:2319-2323

    CAS  PubMed  Google Scholar 

  20. Rives N, Sibert L, Clavier B, Delabroye V, Marpeau L, Mace B (1998) Full-term delivery following intracytoplasmic sperm injection with frozen-thawed immotile testicular spermatozoa. Hum Reprod 13:3399-3401

    Article  CAS  PubMed  Google Scholar 

  21. Patrizio P, Ord T, Balmaceda JP, Asch R (1995) Successful fertilization, pregnancy and birth using epididymal sperm frozen 24 hours after conventional oocyte insemination. Fertil Steril 64:863-865

    CAS  PubMed  Google Scholar 

  22. Lansac J, Royere D (2001) Follow-up studies of children born after frozen sperm donation. Hum Reprod 7:33-37

    Article  CAS  Google Scholar 

  23. Gandini L, Lombardo F, Lenzi A, Spano M, Dondero F (2006) Cryopreservaiton and sperm DNA integrity. Cell Tiss Bank 7:91-98

    Article  CAS  Google Scholar 

  24. David G, Czyglick F, DaLage C, Alnot MO, Dadoune JP, Auger J, Thepot F, Boulanger JC, Bugnon C, Clavequin MC, Meunier J, Berjeon J, Izard J, Sauvalle A, Boucher D, Janny J, Jalbert P, Servoz-Gavin M, Delecour M (1989) Artificial procreation with frozen donor semen: Experience of the French Federation CECOS. Hum Reprod 4:757-761

    Google Scholar 

  25. U.S. Congress OTA (1988) Artificial insemination practice in the United States: Summary of a 1987 survey: background paper. OTA-BP-BA-48. Washington, DC. U.S. Government Printing Office

    Google Scholar 

  26. McLaughlin EA (2002) Cryopreservation, screening and storage of sperm the challenges for the twenty-first century. Hum Fertil 5:S61-S65

    Article  Google Scholar 

  27. Payne MA, Lamb EJ (2004) Use of frozen semen to avoid human immunodeficiency virus type 1 transmission by donor insemination: A cost effective analysis. Fertil Steril 81:80-92

    Article  PubMed  Google Scholar 

  28. del Mar Perez M, Marina S, Egozcue J (1990) Karyotype screening of potential sperm donors for artificial insemination. Hum Reprod 5:282-285

    Google Scholar 

  29. Scheib JE, Cushing RA (2007) Open-identity donor insemination in the United States. Is it on the rise? Fertil Steril 88:231-232

    Article  Google Scholar 

  30. Daniels K, Feyles V, Nisker J, perez-v-Perez M, Newton C, Parker JA, Tekpetev F, Haase J (2006) Sperm donation: implications of Canada’s assisted human reproduction act 2004 for recipients, donors, health professionals and institutions. J Obstet Gynaecol Can 28:608-615

    CAS  PubMed  Google Scholar 

  31. HFEA (1997) Sixth Annual Report, Human fertilisation and embryology Authority, London

    Google Scholar 

  32. Weissenberg R, Landau R, Madgar I (2007) Older single mothers assisted by sperm donation and their children. Hum Reprod 22:2784-2791

    Article  CAS  PubMed  Google Scholar 

  33. Keel BA, Webster BW (1989) Semen analysis data from fresh and cryopreserved donor ejaculated: Comparison of cryoprotectants and pregnancy rates. Fertil Steril 52:100-105

    CAS  PubMed  Google Scholar 

  34. Nallella KP, Sharma RK, Said TM, Agarwal A (2004) Inter-sample variability in post-thaw human spermatozoa. Cryobiology 49:195-199

    Article  PubMed  Google Scholar 

  35. Centola GM, Raubertas RF, Mattox JH (1992) Cryopreservation of human semen: Comparison of cryopreservatives, sources of variability and prediction of post-thaw survival. J Androl 13:283-288

    CAS  PubMed  Google Scholar 

  36. Mazur P (1993) Fundamental cryobiology. In: 1993 Regional Postgraduate Course. Cryopreservation of spermatozoa and embryos. The American Fertility Society, Birmingham, AL, pp 1-32

    Google Scholar 

  37. Prins GS, Weidel L (1986) A comparative study of buffer systems as cryoprotectants for human spermatozoa. Fertil Steril 46:147

    CAS  PubMed  Google Scholar 

  38. Hossain AM, Osuamkpe CO (2007) Sole use of sucrose in human sperm cryopreservation. Arch Androl 53:99-103

    Article  CAS  PubMed  Google Scholar 

  39. Mahadevan M, Trouson AO (1983) Effect of cryopreservative media and dilution methods on the preservation of human spermatozoa. Andrologia 15:355-366

    Article  CAS  PubMed  Google Scholar 

  40. Stanic P, Tandara M, Sonicki Z, Simunic V, Radakovic B, Suchanek E (2000) Comparison of protective media and freezing techniques for cryopreservation of human semen. Eur J Obstet Gynecol Reprod Biol 91:65-70

    Article  CAS  PubMed  Google Scholar 

  41. Hammadeh ME, Dehn C, Hippach M, Zeginiadou T, Steiber M, Georg T, Rosenbaum P, Schmidt W (2001) Comparison between computerized slow-stage and static liquid nitrogen vapour freezing methods with respect to the deleterious effect on chromatin and morphology of spermatozoa from fertile and subfertile men. Int J Androl 24:66-72

    Article  CAS  PubMed  Google Scholar 

  42. Keros V, Rosenlund B, Hultenby K, Aghajanova L, Levkov L, Hovatta O (2005) Optimizing cryopreservation of human testicular tissue: Comparison of protocols with glycerol, propanediol and dimethylsulphoxide as cryoprotectants. Hum reprod 20:1676-1687

    Article  CAS  PubMed  Google Scholar 

  43. Keros V, Hultenby K, Borgstron B, Fridstrom M, Jahnukainen K, Hovatto O (2007) Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. Hum Reprod 22:1384-1395

    Article  CAS  PubMed  Google Scholar 

  44. Ortloff C, Deppe M, Schill WB, Sanchez R (2006) A new technique to evaluate the ability of cryoprotectors to prevent premature acrosome reaction in human spermatozoa. Andrologia 38:230-232

    Article  CAS  PubMed  Google Scholar 

  45. Larson JM, McKinney KA, Mixon BA, Burry KA, Wolf DP (1997) An intrauterine insemination-ready cryopreservation method compared with sperm recovery after conventional freezing and post-thaw processing. Fertil Steril 68:143-148

    Article  CAS  PubMed  Google Scholar 

  46. Wolf DP, Patton PE, Burry KA, Kaplan PF (2001) Intrauterine insemination-ready versus conventional semen cryopreservation for donor insemination: a comparison of retrospective results and a prospective, randomized trial. Fertil Steril 76:181-185

    Article  CAS  PubMed  Google Scholar 

  47. Mazzilli F, Delfino M, Imbrogno N, Elia J, Dondero F (2006) Survival of micro-organisms in cryostorage of human sperm. Cell Tissue Banking 7:75-79

    Article  CAS  Google Scholar 

  48. Sherman JK, Rosenfeld J (1975) Importance of frozen-stored human semen in the spread of gonorrhea. Fertil Steril 26:1043-1047

    CAS  PubMed  Google Scholar 

  49. Glander HJ, Schonborn C, Rytter M (1983) Microbiolocial investigations on cryopreserved human semen. Int J Androl 6:358-366

    Article  CAS  PubMed  Google Scholar 

  50. Glander HJ, Schonborn C, Rytter M (1983) Microbioligcal investigations on cryopreserved human semen. Int J Androl 6:358-366

    Article  CAS  PubMed  Google Scholar 

  51. Thorsen P, Moller BR, Halkier-Sorensen L, From E, Nielson NC (1991) Survival of Chlamydia in human semen prepared for artificial insemination by donor. Acta Obstet Gynecol Scand 70:133-135

    Article  CAS  PubMed  Google Scholar 

  52. Sherman JK, Menna JH (1986) Cryosurvival of herpes simplex virus-2 during cryopreservation of human spermatozoa. Cryobiology 23:383-385

    Article  CAS  PubMed  Google Scholar 

  53. Mansat A, Mengelle C, Chalet M, Boumzebra A, Mieusset R, Puel J, Prouheze C, Segondy M (1997) Cytomegalovirus detection in cryopreserved semen samples collected for therapeutic donor insemination. Hum Reprod 12:1663-1666

    Article  CAS  PubMed  Google Scholar 

  54. McKee TA, Avery S, Majid A, Brindsen PR (1996) Risks for transmission of hepatitis C virus during artificial insemination. Fertil Steril 66:161-163

    CAS  PubMed  Google Scholar 

  55. Massey EJ, Dasani H, Jones P, Saleem AK (1996) Storage of sperm and embryos. Storage facility exists for sperm from patients positive for antibody to hepatitis C virus. BMJ 313:1078

    CAS  PubMed  Google Scholar 

  56. Matz B, Kupfer B, Ko Y, Walger P, Vetter H, Eberle J, Gurtler L (1998) HIV-1 infection by artificial insemination. Lancet 351:728

    Article  CAS  PubMed  Google Scholar 

  57. Tedder RS, Gilson RJ, Briggs M, Loveday C, Cameron CH, Garson JA, Kelly GE, Weller IV (1991) Hepatitis C virus: evidence for secual transmission. BMJ 302:1299-1302

    Article  CAS  PubMed  Google Scholar 

  58. Bielanski A, Bergeron H, Lau PC, Devenish J (2003) Microbial contamination of embryos and semen during long term banking in liquid nitrogen. Cryobiology 46:146-152

    Article  CAS  PubMed  Google Scholar 

  59. Lwtur-Konirsch H, Collin G, Sifer C, Devaux A, Kurttenn F, Madelanat P, Brun-Vezinet F, Feldmann F, Benifla JL (2003) Safety of cryopreservation straws for human gametes or embryos: a study with human immunodeficiency virus-1 under cryopreservation conditions. Hum Reprod 18:140-144

    Article  Google Scholar 

  60. Tomlinson M, Sakkas D (2000) Is a review of standard procedures for cryopreservation needed? Safe and effective cryopreservation-should sperm banks and fertility centers move toward storage in liquid nitrogen vapour? Hum Reprod 12:2460-2463

    Article  Google Scholar 

  61. Carrell DT, Wilcox AL, Urry RL (1996) Effect of fluctuations in temperature encountered during handling and shipment of human cryopreserved semen. Andrologia 28:315-319

    Article  CAS  PubMed  Google Scholar 

  62. Centola GM, Mattox J, Raubertas R (1990) Pregnancy rates after double versus single insemination with frozen semen. Fertil Steril 54:1089-1092

    CAS  PubMed  Google Scholar 

  63. Patton PE, Burry KA, Thurmond A, Novy MJ, Wolf DP (1992) Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor semen. Fertil Steril 57:559-564

    CAS  PubMed  Google Scholar 

  64. Matorras R, Pijoan JI, Gorostiaga A, Ramon O, Diez J, Rodriguez-Escudero FJ, Corcostegui B (1996) Intrauterine insemination with frozen sperm increases pregnancy rates in donor insemination cycles under gonadotropin stimulation. Fertil Steril 65:620-625

    CAS  PubMed  Google Scholar 

  65. Patton PE (2005) Optimizing success in a donor insemination program. In: Patton PE, Battaglia DE (eds) Office andrology, Humana Press, Totowa, NJ, pp 91-108

    Chapter  Google Scholar 

  66. Goldberg JM, Mascha E, Falcone T, Attaran M (1999) Comparision of intrauterine and intracervical insemination with frozen donor sperm: A meta-analysis. Fertil Steril 72:792-795

    Article  CAS  PubMed  Google Scholar 

  67. Carroll N, Palmer JR (2001) A comparison of intrauterine versus intracervical insemination in fertile single women. Fertil Steril 75:656-660

    Article  CAS  PubMed  Google Scholar 

  68. Byrd W, Ackerman GE, Bradshaw KD, Maddox MA, Svendsen BA, Carr BR (1991) Comparison of bicarbonate and HEPES-buffered media on pregnancy rates after intrauterine insemination with cryopreserved donor sperm. Fertil Steril 56:540-546

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Cryobank compliance Services, 5125 Delfa Lane, Macedon, NY, USA

    Grace M. Centola

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  1. Grace M. Centola
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Correspondence to Grace M. Centola .

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  1. School of Medicine, University of Utah, Arapeen Dr. 675, Salt Lake City, 84108, USA

    Douglas T. Carrell

  2. School of Medicine, University of Utah, North Medical Drive 50, Salt Lake City, 84132, USA

    C. Matthew Peterson

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Centola, G.M. (2010). Sperm Banking, Donation, and Transport in the Age of Assisted Reproduction: Federal and State Regulation. In: Carrell, D., Peterson, C. (eds) Reproductive Endocrinology and Infertility. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1436-1_33

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  • DOI: https://doi.org/10.1007/978-1-4419-1436-1_33

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