What Is FRAX®?

  • Angelo A. Licata
  • Susan E. Williams


As noted in the chapter about diagnosing osteoporosis (see  Chap. 1), T-scores alone may not be adequate to predict the risk for fragility fractures and diagnose the disease state of osteoporosis because bone density testing only partially explains the risk for fracture. A large part of resistance to fracture or bone strength is related to elements comprising the quality of the skeleton which bone density cannot measure. These characteristics are related to a patient’s age and the microscopic architecture in the bone which are “hidden” from scanning. For the practitioner, these characteristics can be determined from a patient’s age and pertinent historical information.


Fracture Risk Fragility Fracture Clinical Risk Factor Major Osteoporotic Fracture National Osteoporosis Foundation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Angelo A. Licata
    • 1
  • Susan E. Williams
    • 2
  1. 1.Departments of Biomedical Engineering and Endocrinology-MetabolismCleveland ClinicClevelandUSA
  2. 2.Endocrinology, Diabetes and MetabolismThe Cleveland Clinic FoundationClevelandUSA

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