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Dermal Toxicity and Environmental Contamination: Electron Transfer, Reactive Oxygen Species, Oxidative Stress, Cell Signaling, and Protection by Antioxidants

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Book cover Reviews of Environmental Contamination and Toxicology

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 203))

Abstract

Many papers have addressed the role of electron transfer (ET) (electron movement from one site to another), reactive oxygen species (ROS), and oxidative stress (OS) in producing cellular insults and, thereby, toxicity in major organs. The present review provides evidence for the same mechanistic theme as it applies to skin toxicants.

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Acknowledgments

Assistance by Dr. Terence O’Grady, UCSD, as well as by Thelma Chavez, is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, San Diego State University, San Diego, CA, 92182-1030, USA

    Peter Kovacic

  2. Centro de Graduados e Investigación del Instituto Tecnológico de Tijuana, Tijuana, BC, Mexico

    Ratnasamy Somanathan

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  1. Peter Kovacic
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  2. Ratnasamy Somanathan
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Correspondence to Peter Kovacic .

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    David M. Whitacre

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Kovacic, P., Somanathan, R. (2010). Dermal Toxicity and Environmental Contamination: Electron Transfer, Reactive Oxygen Species, Oxidative Stress, Cell Signaling, and Protection by Antioxidants. In: Whitacre, D. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 203. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1352-4_4

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