Antituberculosis BCG Vaccine: Lessons from the Past

  • Marina Gheorgiu


The next decade will celebrate the 100th anniversary of the discovery of the Mycobacterium bovis BCG. As a matter of fact, it was on December 28, 1908 that Albert Calmette and Camille Guérin reported to the Académie des Sciences that they had obtained a new “race of biliated tuberculosis bacilli” [1]. BCG was not discovered by chance. Based on previous knowledge of tuberculosis and earlier tuberculosis vaccines, BCG was about all the result of the dedicated work of these two personalities, who thoroughly studied the changes occurring during their experiments.


Bacillus Anthracis Successive Passage Mycobacterium Bovis Intradermal Route Poultry Cholera 
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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Marina Gheorgiu
    • 1
  1. 1.Laboratoire du BCGInstitut PasteurParis cedex 15France

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