Vaccination Against Varicella and Zoster: Its Development and Progress



At one time in history, it seems, rash diseases tended to be lumped together under the term “pox” and these illnesses must have been very common. Syphilis was known as the “great pox” and smallpox was considered yet another “pox” illness. The well known quotation from Shakespeare’s play, Romeo and Juliet, is usually given as “A pox on both your houses.” In fact however, “A plague on both your houses” is what Shakespeare actually wrote; plague killed 25% of the European population between 1347 and 1348. “Pox” diseases included plague perhaps, as well as smallpox, syphilis, measles, rubella, chickenpox, and more. Eventually, scientific advances would considerably delineate the diversity of the myriad of pathogens that cause human infections manifested by fever and rash.


Necrotizing Fasciitis Leukemic Child Varicella Vaccine Varicella Vaccination Immunocompromised Child 
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© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Department of PediatricsColumbia UniversityNew YorkUSA

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