The Role of Tissue Culture in Vaccine Development

  • Samuel L. Katz
  • Catherine M. Wilfert
  • Frederick C. Robbins


In 1954, John F Enders, Frederick C Robbins and Thomas H Weller received the Nobel Prize in Physiology and Medicine for their successful propagation of poliovirus in tissue culture. Like many great scientific advances, this was the culmination of a lengthy series of laboratory investigations that had begun more that 20 years previously and had included the work of a great number of scientists. The publication by the Enders’ group in 1949 of their seminal work provided the “Rosetta Stone” that integrated the results of previous research and added those techniques necessary to its final completion and widespread applicability [1].


Nobel Prize Cell Culture System Japanese Encephalitis Mumps Virus Widespread Applicability 
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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Samuel L. Katz
    • 1
  • Catherine M. Wilfert
  • Frederick C. Robbins
  1. 1.Duke University School of MedicineDurhamUSA

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