A Novel Approach to Evaluate the Vessel Function Determined by Near Infrared Spectroscopy

  • Hajime MiuraEmail author
  • Nao Okumura
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 662)


The purpose of this study was to evaluate arterial function by near infrared spectroscopy (NIRS). 16 elderly subjects were studied: 8 were arteriosclerosis obliterans patients (ASO), and 8 were healthy elderly (non-ASO). A cuff around the thigh was inflated to a pressure of 20% above their ankle systolic blood pressure for 3 min. The NIRS probe was positioned over the gatrocnemius muscle to measure oxygenated hemoglobin (O2Hb), and the recovery time and rate for ΔO2Hb after occlusion were calculated. Compared with the non-ASO group, the ASO group had a longer recovery time (p < 0.05) and a shallower recovery rate gradient (p < 0.01). The ankle to brachial index was correlated with recovery time (r = −0.61, p < 0.01) and recovery rate (r = 0.80, p < 0.001). These data suggest that NIRS may provide an effective non-invasive method for evaluating arterial function in patients with arteriosclerosis obliterans.


Recovery Time Near Infrared Spectroscopy Slow Recovery Simple Linear Regression Analysis Arterial Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We thank Yoshinori Takahashi and Maiko Fujisawa for their technical assistance in this study. This study was supported by a grant from Meiji Yasuda Life Foundation of Health and Welfare.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Laboratory for Applied Physiology, Faculty of Integrated Arts and SciencesUniversity of TokushimaTokushimaJapan

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