Effects of Acute Hypoxia on the Inflection Point of Muscle Oxygenation

  • Takuya Osawa
  • Ryotaro Kime
  • Toshihito Katsumura
  • Masayoshi Yamamoto
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 662)


The purpose of this study was to investigate the effects of acute hypoxia on the inflection point of muscle oxygenation (IPMO) using near-infrared spectroscopy during incremental bicycle exercise. Eight male subjects (age: 22 ± 2 years) performed two ramp incremental bicycle exercise tests until exhaustion under each normoxic and hypoxic (FIO2: 0.12) condition. Pulmonary gas exchange and locomotor muscle oxygenation were continuously measured. IPMO was determined as the attenuated point of muscle deoxygenation. Muscle oxygenation level was significantly lower in hypoxia than normoxia throughout the tests. IPMO was found in both conditions, and \(\dot {\rm V}{\rm O}_{2{\rm}}\) at IPMO was significantly decreased in hypoxia. However the percent rate of \(\dot {\rm V}{\rm O}_{2{\rm{peak}}}\) between normoxia and hypoxia was not significantly different. These results suggest that IPMO was not associated with absolute exercise intensity, but relative exercise intensity.


Exercise Intensity Ventilation Threshold Acute Hypoxia Muscle Oxygenation Relative Exercise Intensity 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Takuya Osawa
    • 1
  • Ryotaro Kime
    • 1
  • Toshihito Katsumura
    • 1
  • Masayoshi Yamamoto
    • 2
  1. 1.Department of Sports Medicine for Health Promotion, Faculty of MedicineTokyo Medical UniversityTokyoJapan
  2. 2.Research Center for Training Science and Applied PhysiologyNational Institute of Fitness and Sports in KanoyaKagoshimaJapan

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