Individual Differences in Blood Volume and Oxygenation in the Brain during a Cognitive Task based on Time-Resolved Spectroscopic Measurements

  • Tadashi Niioka
  • Soichiro Ohnuki
  • Yoshifumi Miyazaki
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 662)


Although a time-resolved near-infrared spectroscopy (TRS) system is difficult to make a measurement into 10 s or less at the moment, the system has a great advantage that it measures absolute values of hemoglobin concentrations. In the present study, using a device equipped with a TRS system, we examined individual differences in changes in cerebral oxygenated, deoxygenated, and total hemoglobin concentrations during two repetitive executions of a cognitive task, and compared these with data from our previous studies performed with a CWS system. As a result, large individual differences were also observed in changes in the cerebral hemoglobin concentrations during a cognitive task in this study using a TRS system. We therefore conclude that large individual differences observed in changes in the cerebral hemoglobin concentrations during a cognitive task in our previous studies using a continuous wave near-infrared spectroscopy (CWS) system would probably be universal, although a CWS system includes the limitation that the absolute value is unable to be measured in the system.


Cognitive Task Hemoglobin Concentration Cerebral Blood Volume Color Word Total Hemoglobin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



This work was supported in part by Grant-in-Aid for Scientific Research (19570232).


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Tadashi Niioka
    • 1
  • Soichiro Ohnuki
    • 1
  • Yoshifumi Miyazaki
    • 2
  1. 1.Graduate School of Environmental Earth ScienceHokkaido UniversitySapporoJapan
  2. 2.Center for Environment, Health and Field SciencesChiba UniversityKashiwaJapan

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