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Synchronization Between Cardiac and Respiratory Rhythms in Healthy Subjects and Patients

  • Masaki Shimane
  • Yutaka Tomita
  • Toshihiro Shinbo
  • Kenichi Kokubo
  • Minoru Hirose
  • Ryuji Hataishi
  • Hisashi Mitsufuji
  • Masaru Kubota
  • Noriyuki Masuda
  • Hirosuke Kobayashi
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 662)

Abstract

Synchronization between cardiac and respiratory rhythms may be important for oxygen transport to tissues. The aim of this study was to investigate the synchronization between cardiac and respiratory rhythms. We evaluated the rhythms in 12 healthy males and 24 patients. The incidence rates of heart beats were obtained in each time interval relative to the initiation time point of inspiration. A simple index of timing variability of heart beats was defined. When the variability is large, the link between cardiac and respiratory rhythms was considered to be strong. The variability value of patients with disorder in the autonomic nervous system was larger than that of healthy subjects (p < 0.05). The variability of patients on controlled ventilation was lower than that of healthy subjects (p < 0.01), whereas the value on cardiac pacemaker did not differ from healthy subjects. In conclusion, the synchronization between cardiac and respiratory rhythms was confirmed, and it is suggested that the synchronization is enhanced when feed-back signals from respiratory movement to respiratory center were decreased.

Keywords

Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Patient Respiratory Movement Heart Beat Cardiac Rhythm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

We would like to thank Tateo Ogura, Department of Medicine, Kitasato Univ. Hospital, Shuji Ariga and Takanori Hirata, Department of Engineering, Keio University, for their excellent technical assistance, and Naosada Takizawa, Information Science Center, Kitasato Univ. for his technical advice in this study.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Masaki Shimane
    • 1
  • Yutaka Tomita
    • 2
  • Toshihiro Shinbo
    • 3
  • Kenichi Kokubo
    • 3
  • Minoru Hirose
    • 3
  • Ryuji Hataishi
    • 4
  • Hisashi Mitsufuji
    • 4
  • Masaru Kubota
    • 4
  • Noriyuki Masuda
    • 4
  • Hirosuke Kobayashi
    • 3
  1. 1.Department of Respiratory MedicineKitasato University Kitasato Institute Medical Center HospitalSaitamaJapan
  2. 2.Department of Biosciences and InformaticsKeio UniversityKanagawaJapan
  3. 3.Department of Medical Engineering and TechnologySchool of Allied Health Sciences, Kitasato UniversityKanagawaJapan
  4. 4.Department of MedicineKitasato UniversityKanagawaJapan

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