The superior vena cava syndrome in malignancy is most often secondary to lung cancer where up to 10% of patients with small cell lung cancer and 2% with non-small cell lung cancer will have this syndrome. Classically, steroids, chemotherapy, and radiotherapy have been the standards of therapy. However, over the past few years, stenting has mostly replaced these standards as its advantages are rapid efficacy and giving at least equal results for the clinical syndrome in addition to allowing the securing of a biopsy tissue for diagnosis, and the clinical relief of symptoms is almost immediate.
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