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History of RNase P and Overview of Its Catalytic Activity

  • Sidney Altman
Chapter
Part of the Protein Reviews book series (PRON, volume 10)

Abstract

A description of the history of RNase P, including a few of the personal events in the experimental process, is given. The discovery of the catalytic action of the RNA subunit of RNase P from Escherichia coli is also presented in some detail.

Keywords

Protein Subunit Glycerol Gradient Human RNase tRNA Precursor Computer Assisted Model 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

The author thanks profusely all the members of his own laboratory over the years who have contributed their experimental efforts and perceptive discussions that formulated the results from Yale University. The author also thanks Rose Stone for sterling service as an administrative assistant over a period of many years.

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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Molecular, Cellular and Developmental BiologyYale UniversityNew HavenUSA

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