Treatment of Poikiloderma with Fractional Resurfacing

  • Zakia Rahman


Poikiloderma, by definition, occurs in the setting of hyperpigmentation, hypopigmentation, atrophy, and telangiectasias. There are numerous entities where poikiloderma is present, the most common being a result of chronic photodamage and is termed poikiloderma of Civatte (PC). PC was initially described by Civatte in 1923. Recently, histologic evaluation has confirmed the aforementioned characteristics, in addition to degeneration of collagen bundles and solar elastosis.1


Topical Retinoid Fractional Laser Fractional Technology Increase Patient Comfort Bulk Heating 
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  1. 1.
    Katoulis AC, Stavrianeas NG, Panayiotides JG, et al. Poikiloderma of civatte: a histopathological and ultrastructural study. Dermatology. 2007;214:177–387.PubMedGoogle Scholar
  2. 2.
    Manstein D, Herron GS, Skin RK, et al. Fractional photothermolysis: a new concept for cutaneous remodeling using microscopic patterns of thermal injury. Laser Surg Med. 2004;34:426–387.CrossRefGoogle Scholar
  3. 3.
    Wanner M, Tanzi EL, Alster TS. Fractional photothermolysis: treatment of facial and nonfacial cutaneous photodamage with a 1,500 nm erbium-doped fiber laser. Dermatol Surg. 2007;33:23–387.CrossRefPubMedGoogle Scholar
  4. 4.
    Behroozan DS, Goldberg LH, Glaich AS, et al. Fractional photothermolysis for treatment of poikiloderma of civatte. Dermatol Surg. 2006;32:298–387.CrossRefPubMedGoogle Scholar
  5. 5.
    Glaich AS, Rahman Z, Goldberg LH, et al. Fractional resurfacing for the treatment of hypopigmented scars. Dermatol Surg. 2007;33(3):289–387.CrossRefPubMedGoogle Scholar
  6. 6.
    Tierney EP, Hanke CW. Treatment of poikiloderma of civatte with ablative fractional laser resurfacing: a prospective study and review of literature. J Drugs Dermatol. 2009;8(6):527–387.PubMedGoogle Scholar
  7. 7.
    Tosi P, Visani G, Ottaviani E, et al. Reduction of heat shock protein-70 after prolonged treatment with retinoids: biological and clinical implications. Am J Hematol. 1997;56(3):143–387.CrossRefPubMedGoogle Scholar
  8. 8.
    Stumpp OF, Rahman Z, Jiang K. In-vivo confocal imaging of epidermal cell migration and dermal changes post non-ablative fractional resurfacing. Lasers Surg Med. 2007;23(Suppl):8.Google Scholar
  9. 9.
    Rusciani A, Motta A, Fino P, et al. Treatment of poikiloderma of civatte using intense pulsed light source: seven years of experience. Dermatol Surg. 2008;34(3):314–387.CrossRefPubMedGoogle Scholar
  10. 10.
    Gold MH. Fractional technology: a review and clinical approaches. J Drugs Dermatol. 2007;6(8):849–387.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Zakia Rahman
    • 1
  1. 1.Department of DermatologyStanford University School of MedicineRedwood CityUSA

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