Prepackaged Injectable Soft-Tissue Rejuvenation of the Hand and Other Nonfacial Areas

  • William Philip Werschler
  • Mariano Busso


The presence of soft tissue fillers in aesthetic surgery has grown exponentially since the introduction of botulinum toxin A into the aesthetic environment in the early 1990s. Representative soft tissue fillers currently seen in clinician offices include collagens (Cosmoplast®, Zyderm®, Zyplast®), hyaluronic acid compounds (Captique®, HylaForm®, HylaForm Plus®, Juvederm®, Restylane®, Perlane®), poly-L-lactic acid (PLLA; Sculptra®), polymethylmethacrylate (PMMA; Artefill®), and calcium hydroxylapatite (CaHA; Radiesse®). The last filler mentioned here is a soft tissue filler increasingly referenced in the clinical literature and the one described in detail herein for the soft tissue augmentation of nonfacial areas.


Botulinum Toxin Post Injection Clinician Office Aesthetic Surgery Extrusion Force 
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The authors express appreciation to BioForm Medical researcher staff members Robert Voigts, Dale DeVore, PhD, Michelle Johnson, and Xanthi Merlo for their studies on the properties of CaHA. The authors also thank the editors of the Journal of Dermatologic Therapy for permission to use images and some text that appeared earlier in their journal. Finally, the authors value the editorial assistance provided by David J. Howell, PhD, San Francisco, CA.

Disclosures . Dr. Werschler is an advisory board member, clinical investigator, consultant, investor, and/or speaker for Allergan, Inc, Artes, BioForm Medical, Inc, DermAvance Pharmaceuticals, Inc, Johnson & Johnson, MyoScience Inc, Medicis Pharmaceutical Corporation, Revance Therapeutics, and Sanofi-Aventis.

Dr. Busso has been an investigator for Radiesse and ArteFill clinical trials; he is a member of the BioForm Medical Education Faculty. He is also on advisory boards for Dermik and Allergan.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • William Philip Werschler
    • 1
    • 2
  • Mariano Busso
    • 3
    • 4
  1. 1.Department of DermatologyUniversity of Washington School of MedicineSeattleUSA
  2. 2.Spokane Dermatology ClinicSpokaneUSA
  3. 3.Department of Dermatology and Cutaneous SurgeryUniversity of Miami, Miller School of MedicineMiamiUSA
  4. 4.Private PracticeCoconut GroveUSA

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