Abstract
Liposuction is the aesthetic removal of undesirable, localized collections of subcutaneous adipose tissue.1 An individual may be near his or her ideal body weight, yet still have disproportionate, localized adipose deposition. Such a patient is an ideal candidate for tumescent liposuction. This technique of infiltrating large volumes of dilute lidocaine and epinephrine obviated the need for general anesthesia, virtually eliminated the need for blood transfusions, and decreased patient recovery time.2–4 Lidocaine toxicity is the most significant factor that limits the amount of anesthesia used in tumescent liposuction. Using the tumescent technique, lidocaine dosages up to 55 mg/kg can be used with minimal risk of lidocaine toxicity.5
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References
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Appendices
Appendix A: Medications Which Inhibit Cytochrome P450
Drug | Generic name (Trade name) |
Generic name (Trade name) | Miconazole (Micatin) |
Acebutolol (Sectral) | Midazolam (Versed) |
Acetazolamide | Nadolol (Corzide) |
Alprazolam (Xanax) | Naringenin (grapefruit juice) |
Amiodarone (Cordarone) | Nefazodone (Serzone) |
Anastrazole (Arimidex) | Nelfinavir (Viracept) |
Atenolol (Tenoretic) | Nevirapine (Viramune) |
Cannabinoids | Nicardipine (Cardene) |
Carbamazepine (Tegretol) | Nifedipine (Procardia) |
Cimetidine (Tagamet) | Omeprazole (Prilosec) |
Chloramphenicol | Paroxetine (Paxil) |
Clarithromycin (Biaxin) | Pentoxifylline (Trental) |
Cyclosporin (Neoral) | Pindolol |
Danazol (Danocrine) | Propranolol (Inderal) |
Dexamethasone (Decadron) | Propofol (Diprivan) |
Diltiazem (Cardiazam) | Quinidine (Quinaglute) |
Diazepam (Valium) | Remacemide |
Erythromycin | Ritonavir (Norvir) |
Esmolol (Brevibloc) | Saquinavir (Invirase) |
Fluconazole (Diflucan) | Sertinadole |
Fluoxetine (Prozac) | Sertraline (Zoloft) |
Fluvoxamine (Luvox) | Stiripentol |
Norfluoxetine | Tetracycline (Achromycin, Sumycin) |
Flurazepam | Terfenadine (Seldane) (not available) |
Indinivir (Crixivan) | |
Isoniazid (Rifamate) | Thyroxine |
Itraconazole (Sporanox) | Timolol (Blocadren, Cosopt, Timolide) |
Ketoconazole (Nizoral) | Triazolam (Halcion) |
Labetolol (Normodyne, Trandate) | Troglitazon (Rezulin) |
Methadone | Troleandomycin (Tao) |
Methylprednisolone (Solu-Medrol, Depo-Medrol) | Valproic Acid (Depakote) |
Metroprolol (Toprol-XL) | Verapamil (Calan) |
Metronidazole (Flagyl) | Zafirlukast (Accolate) |
Mibefradil (Posicor) | Zileuton (Zyflo) |
Modified from Shiffman M. Medication potentially causing lidocaine toxicity. Am J Cosmet Surg. 1998:227-229. McEvoy GK, ed. AHFS drug information. Bethesda, MD: 2000. Gelman CR, Rumack BH, Hess AJ, eds. Drugdex R. System. Englewood, CO: Micromedex Inc; 2000.
Appendix B: Medications that May Affect Bleeding
Patient to avoid use of these agents 2 weeks prior to liposuction
Accutane-Alert MD | Ecotrin |
---|---|
Advil | Empirin |
Alka-Seltzer Tablets | Emperin with Codeine |
Alka-Seltzer Plus Cold Medicine | Emprazil-C Tablets |
Anacin Capsules and Tablets | Equagesic |
Anacin Maximum Strength Capsules/Tabs | Excedrin |
APC Tablets | Fiorinal with Codeine |
APC with Codeine, Tabloyd Brand | Four (4)-Way Cold Tablets |
Arthritis Formula by the makers of | Gemnisyn |
Anacin Tablets | Goody’s Headache Powders |
Ascodeen-30 | Ibuprofen |
Ascriptin | Indocin |
Aspirin | Measurin |
Aspergum | Midol |
Aspirin Suppositories | Momentum Muscular Backpain Formula |
Anarox | Monacet with Codeine |
Bayer Aspirin | Motrin |
Bayer Children’s Chewable Aspirin | Naprosyn |
Bayer Children’s Cold Tablets | Norgesic/Norgesic Forte |
Bayer Timed-Released Aspirin | Norwich Aspirin |
BC Powders | Pabirin Buffered Tablets |
Buff-a Comp Tablets | Panalgesic/Percodan/Percodan Demi tabs |
Buffadyne | Persistin |
Bufferin | Quiet World Analgesic/Sleeping Aid |
Bufferin Feldene | Robaxisal Tablets |
Butalbital | Salsalate |
Cama Inlay Tablets | SK-65 Compound |
Cetased, Improved | St. Joseph’s Aspirin for Children |
Cheracol Capsules | Sine-Aid |
Clinoril | Sine-Off Sinus Medicine/Aspirin Formula |
Congespirin | Stendin |
Cope | Stero-Darvon with Aspirin |
Coricidin D Decongestant Tablets | Sulindac |
Coricidin Medilets Tablets for Children | Supac |
Darvon | Synalgos Capsules |
Darvon with Aspirin | Tolectin |
Darvon-N with Aspirin | Triamcinilin |
Dristan Decongestant Tablets/Capsules | Verin |
Duragesic | Viromed Tablets |
Vitamin E |
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Jacob, C.I. (2010). Body Contouring with Tumescent Liposuction. In: Alam, M., Pongprutthipan, M. (eds) Body Rejuvenation. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1093-6_25
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DOI: https://doi.org/10.1007/978-1-4419-1093-6_25
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