Abstract
Dural-based neoplasms derived from meningothelial (arachnoid) cells including a wide variety of histologic subtypes, ranging from benign WHO grade I variants to more biologically aggressive meningiomas encompassing WHO grades II and III. Many pediatric meningiomas are sporadic; however, a significant proportion arise in the context of a hereditary cancer predisposition syndrome, especially Neurofibromatosis type 2 (NF2). Multiplicity of meningiomas is not uncommon in NF2, and the pediatric onset of meningioma should prompt further evaluation for clinical and genetic findings diagnostic of NF2. Meningiomas are infrequently encountered with Gorlin syndrome. Exposure to radiotherapy for prior neoplasm is another significant predisposing factor in the development of meningiomas, particularly within the pediatric age group.
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Fuller, C., Pavlovitz, B. (2010). Meningiomas. In: Adesina, A., Tihan, T., Fuller, C., Poussaint, T. (eds) Atlas of Pediatric Brain Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1062-2_9
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DOI: https://doi.org/10.1007/978-1-4419-1062-2_9
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