Pleomorphic Xanthoastrocytoma

  • Christine E. Fuller


PXAs are almost always supratentorial and superficially situated within the cerebral hemispheres (most commonly the temporal or parietal lobe) with involvement of the leptomeninges.

Rare sites include the cerebellum, spinal cord, thalamus, and cerebellopontine angle.

Seventy percent arise as a cyst with solid mural nodule, the remainder being predominantly solid with variable small cystic areas.

Their solid component is iso- to hypodense on CT, isointense on T1-weighted MR imaging, mildly hyperintense on T2-weighted imaging, and strongly enhances following gadolinium administration (Fig. 2.1a and b).

Intratumoral hemorrhage or calcifications are uncommon; peritumoral edema may be present, but is typically minimal.

They may rarely show multifocality or leptomeningeal dissemination.


Pilocytic astrocytoma Pilomyxoid astrocytoma Tanycyte Tanycytoma 

Suggested Reading

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Christine E. Fuller
    • 1
  1. 1.Department of PathologyVirginia Commonwealth UniversityRichmondUSA

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