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Melanocytic Lesions

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Abstract

Dural-based lesions thought to derive from the leptomeningeal melanocytes. These include both circumscribed mass lesions melanocytoma and malignant melanoma, as well as diffuse leptomeningeal melanocytosis and its malignant counterpart melanomatosis. Diffuse melanocytosis is strongly linked to the rare congenital autosomal dominant phakomatosis neurocutaneous melanosis (Touraine syndrome), the affected patients in addition harbor large and/or multiple cutaneous congenital nevi. These patients are at significantly heightened risk for development of leptomeningeal melanoma or melanomatosis.

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Suggested Readings

  • Ahluwalia S, Ashkan K, Casey AT (2003) Meningeal melanocytoma: clinical features and review of the literature. Br J Neurosurg 17(4):347–351

    Article  PubMed  CAS  Google Scholar 

  • Alcutt D, Michowiz S, Weitzman S, Becker L, Blaser S, Hoffman H et al (1993) Primary leptomeningeal melanoma: an unusually aggressive tumor in childhood. Neurosurgery 32(5):721–729

    Article  Google Scholar 

  • Brat D, Giannini C, Scheithauer BW, Burger PC (1999) Primary melanocytic neoplasms of the central nervous system. Am J Surg Pathol 23(7):745–754

    Article  PubMed  CAS  Google Scholar 

  • Chen KT (2003) Crush cytology of melanocytoma of the spinal cord. A case report. Acta Cytol 47(6):1091–1094

    Article  PubMed  Google Scholar 

  • Kadonaga JN, Frieden IJ (1991) Neurocutaneous melanosis: definition and review of the literature. J Am Acad Dermatol 24(5):747–755

    Article  PubMed  CAS  Google Scholar 

  • Lopez-Castilla J, Diaz-Fernandez F, Soult JA, Munoz M, Barriga R (2001) Primary leptomeningeal melanoma in a child. Pediatr Neurol 24(5):390–392

    Article  PubMed  CAS  Google Scholar 

  • Makin GW, Eden OB, Lashford LS, Moppett J, Gerrard MP, Davies HA et al (1999) Leptomeningeal melanoma in childhood. Cancer 86(5):878–886

    Article  PubMed  CAS  Google Scholar 

  • Nicolaides P, Newton RW, Kelsey A (1995) Primary malignant melanoma of meninges: atypical presentation of subacute meningitis. Pediatr Neurol 12(2):172–174

    Article  PubMed  CAS  Google Scholar 

  • O’Brien DF, Crooks D, Mallucci C, Javadpour M, Williams D, du Plessis D et al (2006) Meningeal melanocytoma. Child’s Nerv Syst 22(6):556–561

    Article  Google Scholar 

  • Reyes-Mugica M, Chou P, Byrd S, Ray V, Castelli M, Gattuso P et al (1993) Nevomelanocytic proliferations in the central nervous system of children. Cancer 72(7):2277–2285

    Article  PubMed  CAS  Google Scholar 

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Fuller, C.E. (2010). Melanocytic Lesions. In: Adesina, A., Tihan, T., Fuller, C., Poussaint, T. (eds) Atlas of Pediatric Brain Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1062-2_11

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  • DOI: https://doi.org/10.1007/978-1-4419-1062-2_11

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-1061-5

  • Online ISBN: 978-1-4419-1062-2

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