Physiological Properties of Hippocampal Neurons
Neurons are the basic computational units of the nervous system. Information processing in the brain is critically dependent on the electrophysiological properties of individual neurons, which are determined by the presence and distribution of many functionally and pharmacologically different ion channels. The parameters that define the functional roles of individual neurons can be grouped into two major groups: on the one side are cellular morphology and topology, which dictate the connectivity of each neuron; on the other side are the different electrophysiological properties of each cell type, which are defined by the combined effects of neuronal active and passive properties and shape the integrative function of each individual cell. The type and timing of neuronal responses to synaptic inputs depend on the firing pattern of each neuron, which in turn is set by the interplay of intrinsic and synaptic electrophysiological properties.
KeywordsPyramidal Neuron Potassium Current Sodium Current Basket Cell Axon Initial Segment
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