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What Can We Learn from the Retina in Severe Malaria?

  • Simon J. Glover
  • Kondwani Kawaza
  • Yamikani Chimalizeni
  • Malcolm E. Molyneux
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 659)

Abstract

Plasmodium falciparum malaria can cause death through a variety of complications, an important one of these being cerebral malaria (CM). In areas where P. falciparum transmission is intense, deaths from CM tend to occur in children under the age of 8 years – older people being protected by partial immunity. In an endemic area, asymptomatic P. falciparum parasitaemia is common. Therefore, among individuals with any clinical syndrome, a considerable proportion may have parasitaemia that is incidental and not causally related to the illness (Koram and Molyneux, 2007). This frequently leads to diagnostic difficulty. Children presenting with encephalopathy (altered consciousness with or without convulsions), who are parasitaemic may be suffering from cerebral malaria or may have another cause of encephalopathy (e.g. viral or metabolic) with incidental parasitaemia.

Keywords

Bacterial Meningitis Severe Malaria Cerebral Malaria Plasmodium Falciparum Malaria Indirect Ophthalmoscopy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Simon J. Glover
    • 1
    • 2
  • Kondwani Kawaza
    • 3
  • Yamikani Chimalizeni
    • 3
  • Malcolm E. Molyneux
    • 1
    • 2
  1. 1.College of Medicine, University of MalawiBlantyreMalawi
  2. 2.Malawi-Liverpool-Wellcome Trust Clinical Research ProgrammeBlantyreMalawi
  3. 3.Paediatric DepartmentCollege of MedicineBlantyreMalawi

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