Malaria in Pregnancy and the Newborn

  • Stephen J. Rogerson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 659)


Each year, 40% of the world’s population is exposed to the risk of malaria infection. Approximately 500 million people suffer clinical disease episodes of malaria, and around one million die from it. The greater part of the world’s malaria burden falls on Africa, but recent analyses suggest the amount of malaria in Asia has been underestimated (Snow et al., 2005). Five Plasmodium species infect humans: P. falciparum, P. vivax, P. malariae, P. ovale, and P. knowlesi. The last, which is a common parasite of monkeys, has only recently been described as a human pathogen (Singh et al., ), but appears to be quite widespread in South East Asia. The great majority of severe disease episodes and deaths are due to P. falciparum, but it is becoming increasingly clear that P. vivax can also cause severe disease episodes and deaths (Genton et al., ; Tjitra et al., ). The main presentations of severe and life-threatening malaria are severe anaemia, cerebral malaria (unrouseable coma associated with malaria infection) and respiratory distress.


Malaria Infection Cerebral Malaria Fetal Growth Restriction Parasite Prevalence Infected Erythrocyte 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Stephen Rogerson is supported by the National Health and Medical Research Council of Australia and the Malaria in Pregnancy Consortium.


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© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Medicine (RMH/WH)Post Office Royal Melbourne HospitalParkvilleAustralia

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