Current Status of Treatment of Hepatitis B in Children
Viral Hepatitis B is the cause of significant disease worldwide. Acute infection occurs with hepatitis B, but chronic asymptomatic infection leading to chronic liver disease and hepatocellular carcinoma is a life long concern.
The natural history of hepatitis B (HBV) is well established in adults, but the long-term outcome for children is unclear. The main mechanism of infection in childhood is perinatal transmission, which can be prevented effectively by vaccination.