Imaging of Inflammatory Bowel Disease in Children

  • Sudha Anupindi
  • Rama Ayyala
  • Judith Kelsen
  • Petar Mamula
  • Kimberly E. Applegate

Key Points

■ Children with clinically suspected IBD should have both upper and lower endoscopies as part of the initial workup (strong evidence). Fluoroscopic small bowel follow-through studies are typically performed as part of the initial diagnosis (limited evidence).

■ Wireless capsule endoscopy (WCE) is a safe, moderately sensitive test for the detection of small bowel inflammatory changes and should be utilized in patients without small bowel obstruction and when other diagnostic small bowel exams are negative. However, the specificity and positive predictive value need to be further established (limited evidence).

■ MRI is superior to CT and is the preferred initial diagnostic and follow-up imaging exam of perirectal and perianal disease in Crohn’s disease (CD) patients (moderate–strong evidence).

■ About 70–80% of CD patients and 30–40% of UC patients will require surgery for disease refractory to medical therapy, or severe disease with complications, or risk of malignancy (UC) (moderate evidence).

■ Repeat imaging with SBFT and CT results in significant ionizing radiation exposure and risk of later cancer induction so that alternative imaging methods, MRI and US, should be used (limited evidence).


Inflammatory Bowel Disease Small Bowel Ulcerative Colitis Small Bowel Obstruction Primary Sclerosing Cholangitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Sudha Anupindi
    • 1
  • Rama Ayyala
    • 2
  • Judith Kelsen
    • 3
  • Petar Mamula
    • 4
  • Kimberly E. Applegate
    • 5
  1. 1.Department of Radiology at the Children’s Hospital of PhiladelphiaUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.Department of Internal MedicineMount Sinai Medical CenterNew YorkUSA
  3. 3.Department of PediatricsChildren’s Hospital of PhiladelphiaPhiladelphiaUSA
  4. 4.Department of PediatricsUniversity of Pennsylvania School of Medicine, Children’s Hospital of PhiladelphiaPhiladelphiaUSA
  5. 5.Department of RadiologyEmory University School of MedicineAtlantaUSA

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