Schizophrenia as a Cognitive Disorder: Recent Approaches to Identifying its Core Cognitive Components to Aid Treatment Development

  • Keith H. Nuechterlein
  • Michael F. Green
  • Robert S. Kern


In recent years the central role of cognitive deficits in schizophrenia has been increasingly accepted (Gold & Green, 2005; Green & Nuechterlein, 1999), so much so that the cognitive deficits have become very prominent new targets for treatment development (Gold, 2004; Hyman & Fenton, 2003). In this paper we examine factors that led to the conclusion that cognitive factors are core features of schizophrenia and then discuss recent approaches to identifying the cognitive domains and processes that offer promise as treatment targets.


Cognitive Deficit Cognitive Domain Schizophrenia Patient Cognitive Neuroscience Everyday Functioning 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Keith H. Nuechterlein
    • 1
  • Michael F. Green
    • 2
  • Robert S. Kern
    • 2
  1. 1.Department of Psychiatry and Biobehavioral SciencesUniversity of California, Los Angeles, Semel Institute for Neuroscience and Human BehaviorLos AngelesUSA
  2. 2.Department of Psychiatry and Biobehavioral SciencesSemel Institute for Neuroscience and Human Behavior, University of California; Mental Illness Research, Education, and Clinical Center, VISN 22, VA Greater Los Angeles Healthcare SystemLos AngelesUSA

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