Skip to main content

Acute Pain Control in Geriatric Patients After Cardiac and Thoracic Surgeries

  • Chapter
  • First Online:
Cardiothoracic Surgery in the Elderly

Abstract

Inadequately managed pain in elderly patients undergoing thoracic or cardiac surgery can lead to increased morbidity and mortality, increased length of stay in the intensive care unit and the hospital. Even video-assisted procedures or minimally invasive procedures have not eliminated the problem of pain management. Elderly patients are not less sensitive to pain but are more sensitive to the side effects of analgesics and adjuvants, making titration more difficult. Other means of pain control such as the employment of epidural or intrathecal local anesthetics and opioids, paravertebral catheters with the infusion of local anesthetics offer significant benefits in the overall management of these patients. In this chapter, different means of pain control in this population will be reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Brennan F, Carr D, Cousins M. Pain management: a fundamental human right. Anesth Analg. 2007;105:205–21.

    Article  PubMed  Google Scholar 

  2. Rathmell JP, Wu CL, Sinatra RS, et al. Acute post-surgical pain management: A critical appraisal of current practice. Reg Anesth Pain Med. 2006;31(4 suppl 1):1–42.

    PubMed  Google Scholar 

  3. Gagliese L, Gauthier LR, Macpherson AK, Jovellanos M, Chan YW. Correlates of postoperative pain and intravenous patient-controlled analgesia use in younger and older surgical patients. Pain Med. 2008;3:299–314.

    Article  Google Scholar 

  4. Apfelbaum JL, Chen C, Mehta SS, Gan TJ. Postoperative pain experience: Results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg. 2003;97(2):534–40.

    Article  PubMed  Google Scholar 

  5. Frasco PE, Sprung J, Trentman TL. The impact of the Joint Commission for Accreditation of Healthcare Organizations pain initiative on perioperative opiate consumption and recovery room length of stay. Anesth Analg. 2005;100:162–8.

    Article  PubMed  Google Scholar 

  6. Stafford-Smith M. McLoughlin T. In: Hensley F, Martin D, Gravlee G, editors. A practical approach to cardiac anesthesia. 4th ed. Philadelphia: Lippincott, Williams & Wilkins; 2008. p. 741–56.

    Google Scholar 

  7. Perkins F, Kehlet H. Chronic pain as an outcome of surgery: a review of predictive factors. Anesthesiology. 2000;93:1123–33.

    Article  PubMed  CAS  Google Scholar 

  8. Katz J, Jackson M, Kavanagh B, Brian P, Sandler A. Acute pain after thoracic surgery predicts long-term post-thoracotomy pain. Clin J Pain. 1996;12(1):50–5.

    Article  PubMed  CAS  Google Scholar 

  9. Macrae WA. Chronic pain after surgery. Br J Anaesth. 2001;87:88–98.

    Article  PubMed  CAS  Google Scholar 

  10. Landreneau RJ, Mack MJ, Hazelrigg SR, et al. Prevalence of chronic pain after pulmonary resection by thoracotomy or video-assisted thoracic surgery. J Thorac Cardiovasc Surg. 1994;107: 1079–85.

    PubMed  CAS  Google Scholar 

  11. Bertrand PC, Regnard JF, Spaggiari L, et al. Immediate and long-term results after surgical treatment of primary spontaneous pneumothorax by VATS. Ann Thorac Surg. 1996;61:1641–5.

    Article  PubMed  CAS  Google Scholar 

  12. Sinatra R. Role of COX-2 inhibitors in the evolution of acute pain management. J Pain Symptom Manage. 2002;24(1 suppl):S18–27.

    Article  PubMed  CAS  Google Scholar 

  13. Hopf HW, Hunt TK, West JM, et al. Wound tissue oxygen tension predicts the risk of wound infection in surgical patients. Arch Surg. 1997;132(9):997–1004.

    Article  PubMed  CAS  Google Scholar 

  14. Page GG, Blakely WP, Ben-Eliyahu S. Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats. Pain. 2001;90:191–9.

    Article  PubMed  CAS  Google Scholar 

  15. Carr D, Goudas L. Acute pain. Lancet. 1999;353:2052–8.

    Google Scholar 

  16. Davies HTO, Crombie IK, Macrae WA, Rogers KM. Pain clinic patients in northern Britain. Pain Clin. 1992;5:129–35.

    Google Scholar 

  17. Siddall P, Cousins M. Persistent pain as a disease entity: implications for clinical management. Anesth Analg. 2004;99:510–20.

    Article  PubMed  Google Scholar 

  18. Chung F, Mezei G, Tong D. Adverse events in ambulatory surgery: a comparison between elderly and younger patients. Can J Anesth. 1999;46(4):309–21.

    Article  PubMed  CAS  Google Scholar 

  19. McCleane G. Pain and the elderly patient, Chapter 1. In: McCleane G, Smith H, editors. Clinical management of the elderly patient in pain. New York: The Haworth Medical Press; 2006.

    Google Scholar 

  20. Gagliese L, Melzack R. The assessment of pain in the elderly. In: Lomrang J, Mostofsky D, editors. Handbook of pain and aging. New York: Plenum Press; 1997. p. 69–96.

    Google Scholar 

  21. Gibson S, Farrell M. A review of age differences in the neurophysiology of nociception and the perceptual experience of pain. Clin J Pain. 2004;20(4):227–39.

    Article  PubMed  Google Scholar 

  22. Shin S, Eisenach J. Peripheral nerve injury sensitizes the response to visceral distension but not its inhibition by the antidepressant Milnacipran. Anesthesiology. 2004;100(3):671–5.

    Article  PubMed  CAS  Google Scholar 

  23. Siddall P, Cousins M. Introduction to pain mechanisms: Implications for neural blockade, chapter 23.1. In: Cousins M, Bridenbaugh P, editors. Clinical anesthesia and management of pain. 3rd ed. Philadelphia: Lippincott-Raven; 1998. p. 687.

    Google Scholar 

  24. Berger JM. Acute post-operative pain management in the elderly. In: Rosenthal RA, Zenilman ME, Katlie MR, editors. Principles and practice of geriatric surgery. 2nd ed. New York: Springer; 2010.

    Google Scholar 

  25. Auburn F, Monsel S, Langeron O, Coriat P, Riou B. Post operative titration of intravenous morphine in the elderly patient. Anesthesiology. 2002;96:17–23.

    Article  Google Scholar 

  26. Daykin A, Bowen D, Daunders D, Norman J. Respiratory depression after morphine in the elderly. Anaesthesia. 1986;41:910–4.

    Article  PubMed  CAS  Google Scholar 

  27. Cepeda M, Farrar J, Baumbarten M, Boston R, Carr D, Strom B. Side effects of opioids during short-term administration: effect of age, gender, and race. Clin Pharmacol Ther. 2003;74:102–12.

    Article  PubMed  CAS  Google Scholar 

  28. Fine P, Ashburn M. Functional neuroanatomy and nociception, chapter 1. In: Ashburn M, Rice L, editors. The management of pain. New York: Churchill Livingston; 1998. p. 1–16.

    Google Scholar 

  29. Cousins MJ. Visceral pain. In: Anderson S, Bond M, Mehta M, Swerdlow M, editors. Chronic non-cancer pain: assessment and practical management. Lancaster: MTP Press; 1987.

    Google Scholar 

  30. Malliani A. The conceptualization of cardiac pain as a nonspecific and unreliable alarm system, chapter 4. In: Gebhart G, editor. Visceral pain: progress in pain research and management, vol. 5. Seattle: WA. IASP Press; 1995. p. 63–74.

    Google Scholar 

  31. Dajczman E, Gordon A, Kreisman H, Wolkove N. Long-term postthoracotomy pain. Chest. 1991;99:270–4.

    Article  PubMed  CAS  Google Scholar 

  32. Ochroch EA, Gottschalk A, Augostides J, et al. Long-term pain and activity during recovery from major thoracotomy using thoracic epidural analgesia. Anesthesiology. 2002;97:1234–44.

    Article  PubMed  Google Scholar 

  33. Latremoliere A, Woolf CJ. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain. 2009;9: 895–926.

    Google Scholar 

  34. Scawn ND, Pennefather SH, Soorae A, Wang JY, Russell GN. Ipsilateral shoulder pain after thoracotomy with epidural analgesia: the influence of phrenic nerve infiltration with lidocaine. Anesth Analg. 2001;93:260–4.

    PubMed  CAS  Google Scholar 

  35. Tan N, Agnew NM, Scawn ND, et al. Suprascapular nerve block for ipsilateral shoulder pain after thoracotomy with thoracic epidural analgesia: a double-blind comparison of 0.5% bupivacaine and 0.9% saline. Anesth Analg. 2002;94:199–202.

    PubMed  CAS  Google Scholar 

  36. Benedetti F, Vighetti S, Ricco C, et al. Neurophysiologic assessment of nerve impairment in posterolateral and muscle-sparing thoracotomy. J Thorac Cardiovasc Surg. 1998;115:841–7.

    Article  PubMed  CAS  Google Scholar 

  37. Gottschalk A, Cohen S, Yang S, Ochroch ES. Preventing and treating pain after thoracic surgery. Anesthesiology. 2006;104(3): 594–600.

    Article  PubMed  Google Scholar 

  38. Obata H, Saito S, Fujita N, Fuse Y, Ishizaki K, Goto F. Epidural block with mepivacaine before surgery reduces long-term post-thoracotomy pain. Can J Anaesth. 1999;46:1127–32.

    Article  PubMed  CAS  Google Scholar 

  39. Soto R, Fu ES. Acute pain management for patients undergoing thoracotomy. Ann Thorac Surg. 2003;75:1349–57.

    Article  PubMed  Google Scholar 

  40. Richardson J, Lönnqvist PA. Thoracic paravertebral block. Br J Anaesth. 1998;81:230–8.

    Article  PubMed  CAS  Google Scholar 

  41. Mann C, Pouzeratte Y, Bocarra G, et al. Comparison of intravenous or epidural patient-controlled analgesia in the elderly after major abdominal surgery. Anesthesiology. 2000;92(2):433–41.

    Article  PubMed  CAS  Google Scholar 

  42. Carli F, Mayo N, Klubien K, Schricker T, Trudel J, Belliveau P. Epidural analgesia enhances functional exercise capacity and health related quality of life after colonic surgery. Results of a randomized trial. Anesthesiology. 2002;97(3):540–9.

    Article  PubMed  Google Scholar 

  43. Viscusi E. Emerging techniques in the management of acute pain: epidural analgesia. Anesth Analg. 2005;101:S23–9.

    Article  PubMed  Google Scholar 

  44. Rawal N, Wattwil M. Respiratory depression after epidural morphine – an experimental and clinical study. Anesth Analg. 1984;63:8–14.

    PubMed  CAS  Google Scholar 

  45. Doblar DD, Muldoon SM, Abbrecht PH, Baksoff J, Watson RL. Epidural morphine following epidural local anesthesia: effect on ventilatory and airway occlusion pressure responses to CO2. Anesthesiology. 1981;55:423–8.

    Article  PubMed  CAS  Google Scholar 

  46. Brodner G, Pogatzki E, Van Aken H, et al. A multimodal approach to control postoperative pathophysiology and rehabilitation in patients undergoing abdominothoracic esophagectomy. Anesth Analg. 1998;86:228–34.

    PubMed  CAS  Google Scholar 

  47. Howell SB. Clinical applications of a novel sustained-release injectable drug delivery system: DepoFoam technology. Cancer J. 2001;7:219–27.

    PubMed  CAS  Google Scholar 

  48. DepoDur™(package insert), Bedminster, NJ: EKR Therapeutics Inc; 2007.

    Google Scholar 

  49. Wurnig PN, Lackner H, Teiner C, et al. Is intercostal block for pain management in thoracic surgery more successful than epidural anaesthesia? Eur J Cardiothorac Surg. 2002;21:115–9.

    Article  Google Scholar 

  50. Detterbeck F. Efficacy of methods of intercostal nerve block for pain relief after thoracotomy. Ann Thorac Surg. 2005;80:1550–9.

    Article  PubMed  Google Scholar 

  51. Conacher ID, Kokri M. Postoperative paravertebral blocks for thoracic surgery. A radiological appraisal. Br J Anaesth. 1987;59:155–61.

    Article  PubMed  CAS  Google Scholar 

  52. Lönnqvist PA, MacKenzie J, Soni AK, Conacher ID. Paravertebral blockade. Failure rate and complications. Anaesthesia. 1995;50:813–5.

    Article  PubMed  Google Scholar 

  53. Eng J, Sabanathan S. Site of action of continuous extrapleural intercostal nerve block. Ann Thorac Surg. 1991;51:387–9.

    Article  PubMed  CAS  Google Scholar 

  54. Chan VW, Chung F, Cheng DC, Seyone C, Chung A, Kirby TJ. Analgesic and pulmonary effects of continuous intercostal nerve block following thoracotomy. Can J Anaesth. 1991;38:733–9.

    Article  PubMed  CAS  Google Scholar 

  55. Perttunen K, Nilsson E, Heinonen J, Hirvisalo EL, Salo JA, Kalso E. Extradural, paravertebral and intercostal nerve blocks for post-thoracotomy pain. Br J Anaesth. 1995;75:541–7.

    Article  PubMed  CAS  Google Scholar 

  56. Niamh PC, Andrew DS, Katherine PG. Postthoracotomy paravertebral analgesia: Will it replace epidural analgesia? Anesthesiol Clin. 2008;26(2):369–80.

    Article  Google Scholar 

  57. Richardson J, Sabanathan S, Eng J, et al. Continuous intercostal nerve block versus epidural morphine for postthoracotomy analgesia. Ann Thorac Surg. 1993;55:377–80.

    Article  PubMed  CAS  Google Scholar 

  58. Barron DJ, Tolan MJ, Lea RE. A randomized controlled trial of continuous extra-pleural analgesia post-thoracotomy: efficacy and choice of local anaesthetic. Eur J Anaes. 1999;16:236–45.

    CAS  Google Scholar 

  59. Watson DS, Panian S, Kendall V, Maher DP, Peters G. Pain control after thoracotomy: bupivacaine versus lidocaine in continuous extrapleural intercostal nerve blockade. Ann Thorac Surg. 1999;67:825–9.

    Article  PubMed  CAS  Google Scholar 

  60. Matthews PJ, Govenden V. Comparison of continuous paravertebral and extradural infusions of bupivacaine for pain relief after thoracotomy. Br J Anaesth. 1989;62:204–5.

    Article  PubMed  CAS  Google Scholar 

  61. Bimston DN, McGee JP, Liptay MJ, Fry WA. Continuous paravertebral extrapleural infusion for post-thoracotomy pain management. Surgery. 1999;126:650–7.

    Article  PubMed  CAS  Google Scholar 

  62. Richardson J, Sabanathan S, Jones J, Shah RD, Chesma S, Mearns AJ. A prospective, randomized comparison of preoperative and continuous balanced epidural or paravertebral bupivacaine on post-thoracotomy pain, pulmonary function and stress responses. Br J Anaesth. 1999;83:387–92.

    Article  PubMed  CAS  Google Scholar 

  63. Kaiser AM, Zollinger A, De Lorenzi D, Largiadèr F, Walter W. Prospective, randomized comparison of extrapleural versus epidural analgesia for postthoracotomy pain. Ann Thorac Surg. 1998;66: 367–72.

    Article  PubMed  CAS  Google Scholar 

  64. Berrisford RG, Sabanathan S, Mearns AJ, Clarke BJ, Hamdi A. Plasma concentrations of bupivacaine and its enantiomers during continuous extrapleural intercostal nerve block. Br J Anaesth. 1993;70:201–4.

    Article  PubMed  CAS  Google Scholar 

  65. Dauphin A, Gupta RN, Young JE, Morton WD. Serum bupivacaine concentrations during continuous extrapleural infusion. Can J Anaesth. 1997;44:367–70.

    Article  PubMed  CAS  Google Scholar 

  66. Scott DB. Toxic effects of local anaesthetic agents on the central nervous system. Br J Anaesth. 1986;58:732–5.

    Article  PubMed  CAS  Google Scholar 

  67. Francois T, Blanloeil Y, Pillet F, et al. Effect of interpleural administration of bupivacaine or lidocaine on pain and morphine requirement after esophagectomy with thoracotomy: a randomized, double-blind and controlled study. Anesth Analg. 1995;80:718–23.

    PubMed  CAS  Google Scholar 

  68. Cook D, Rooke G. Priorities in perioperative geriatrics. Anesth Analg. 2003;96:1823–36.

    Article  PubMed  Google Scholar 

  69. Silverstein J, Bloom H, Cassel C. New challenges in anesthesia: new practice opportunities. Anesthesiol Clin North Am. 1999;17:453–65.

    Article  Google Scholar 

  70. Henry C. Mechanisms of changes in basal metabolism during aging. Eur J Clin Nutr. 2000;54:77–91.

    Article  Google Scholar 

  71. Grandison M, Boudinot F. Age-related changes in protein binding of drugs: implications for therapy. Clin Pharmacokinet. 2000;38: 271–90.

    Article  PubMed  CAS  Google Scholar 

  72. Benet L, Kroetz D, Sheiner L. Pharmacokinetics: the dynamics of drug absorption, distribution, and elimination. Chapter 1. In: Hardman J, Limbird L, editors. Goodman & Gilman’s the pharmacological basis of therapeutics. 9th ed. New York: McGraw-Hill; 1996. p. 3–28.

    Google Scholar 

  73. Epstein M. Aging and the kidney. J Am Soc Nephrol. 1996;7: 1106–22.

    PubMed  CAS  Google Scholar 

  74. Lewis M. Alterations in metabolic functions and electrolytes, Chapter 7. In: Silverstein J, Rooke GA, Reves J, McLeskey C, editors. Geriatric anesthesiology. 2nd ed. New York: Springer; 2008. p. 97–106.

    Chapter  Google Scholar 

  75. Svarese A. Intravenous and subcutaneous patient-controlled analgesia. In: Wallace M, Staats P, editors. Pain medicine and management: just the facts. New York: McGraw-Hill; 2004.

    Google Scholar 

  76. Gagliese L, Jackson M, Ritvo P, Wowk A, Katz J. Age is not an impediment to effective use of patient-controlled analgesia by surgical patients. Anesthesiology. 2000;93(3):601–10.

    Article  PubMed  CAS  Google Scholar 

  77. Ginsberg B, Sinatra R, Adler L, Crews J, Hord L, Laurito C, et al. Conversion to oral controlled-release oxycodone from intravenous opioid analgesic in the postoperative setting. Pain Med. 2003;4(1):31–8.

    Article  PubMed  Google Scholar 

  78. Kellet J. Acute soft tissue injuries. A review of the literature. Med Sci Sports Exerc. 1986;18:489–500.

    Google Scholar 

  79. Greenberg HE, Gottesdiener K, Huntington M, et al. A new cyclo-oxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers. J Clin Pharmacol. 2000;40:1509–15.

    PubMed  CAS  Google Scholar 

  80. Mogensen T, Eliasen F, Ejlersen E, Vegger P, Nielsen IK, Kehlet H. Epidural clonidine enhances postoperative analgesia from a combined low-dose epidural bupivacaine and morphine regimen. Anesth Analg. 1992;75:607–10.

    Article  PubMed  CAS  Google Scholar 

  81. Lena P, Balarac N, Arnulf JJ, Teboul J, Bonnet F. Intrathecal morphine and clonidine for coronary artery bypass grafting. Br J Anaesth. 2003;90(3):300–3.

    Article  PubMed  CAS  Google Scholar 

  82. Dowling R, Thielmeier K, Ghaly A, et al. Improved pain control after cardiac surgery: results of a randomized, double-blind, clinical trial. J Thorac Cardiovasc Surg. 2003;126(5):1271–8.

    Article  PubMed  CAS  Google Scholar 

  83. Skubas N, Lichman A, Sharma A, Thomas S. Postoperative pain management, chapter 31. In: Barash PG, Cullen BF, Stoelting RK, editors. Anesthesia for cardiac surgery. 5th ed. Philadelphia: Lippincott Williams & Wilkins; 2006.

    Google Scholar 

  84. Kalso E, Mennander S, Tasmuth T, Nilsson E. Chronic post-­sternotomy pain. Acta Anaesthesiol Scand. 2001;45:935–9.

    Article  PubMed  CAS  Google Scholar 

  85. Scott NB, Turfrey DJ, Ray DA, et al. A prospective randomized study of the potential benefits of thoracic epidural anesthesia and analgesia in patients undergoing coronary artery bypass grafting. Anesth Analg. 2001;93(3):528–35.

    Article  PubMed  CAS  Google Scholar 

  86. Gust R, Pecher S, Gust A, Hoffman V, Böhrer H, Martin E. Effect of patient-controlled analgesia on pulmonary complications after coronary artery bypass grafting. Crit Care Med. 1999;27(10): 2314–6.

    Article  Google Scholar 

  87. Deneuvile M, Bisserier A, Regnard J, Chevalier M, Levasseur P, Herve P. Continuous intercostal analgesia with 0.5% bupivacaine after thoracotomy: a randomized study. Ann Thorac Surg. 1993;55(2):381–5.

    Article  Google Scholar 

  88. Roberge CW, McEwen M. The effects of local anesthetics on postoperative pain. AORN J. 1998;68(6):1003–12.

    Article  PubMed  CAS  Google Scholar 

  89. Gold BS, Kitz DS, Lecky JH, Neuhaus JM. Unanticipated admission to the hospital following ambulatory surgery. JAMA. 1989;262:3008–10.

    Article  PubMed  CAS  Google Scholar 

  90. Mehta Y, Juneja R, Madhok H, Trehan N. Lumbar versus thoracic epidural buprenorphine for postoperative analgesia following coronary artery bypass graft surgery. Acta Anaesthesiol Scand. 1999;43(4):388–93.

    Article  PubMed  CAS  Google Scholar 

  91. Chaney M, Furry P, Fluder E, Slogoff S. Intrathecal morphine for coronary artery bypass grafting and early extubation. Anesth Analg. 1997;85(3):706–7.

    Google Scholar 

  92. Cheong W, Seow-Choen F, Eu K, Tang O, Heah S. Randomized clinical trial of local bupivacaine perfusion versus parenteral morphine infusion for pain relief after laparotomy. Br J Surg. 2001;80:519–20.

    Google Scholar 

  93. Fredman B, Shapiro A, Zohar E, et al. The analgesic efficacy of patient-controlled ropivacaine instillation after cesarean delivery. Anesth Analg. 2000;91(6):1436–40.

    Article  PubMed  CAS  Google Scholar 

  94. Klein S, Grant S, Greengrass R, et al. Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump. Anesth Analg. 2000;91(6):1473–8.

    Article  PubMed  CAS  Google Scholar 

  95. Rosenberg H, Renkonen OV. Antimicrobial activity of bupivacaine and morphine. Anesthesiology. 1985;62(2):178–9.

    Article  PubMed  CAS  Google Scholar 

  96. Mehta Y, Swaminathan M, Mishra Y, Trehan N. A comparative evaluation of intrapleural and thoracic epidural analgesia for postoperative pain relief after minimally invasive direct coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 1999;13(5): 653–5.

    Article  Google Scholar 

  97. Dhole S, Mehta Y, Saxena H, et al. Comparison of continuous thoracic epidural and paravertebral blocks for postoperative analgesia after minimally invasive direct coronary artery bypass surgery. J Cardiothorac Vasc Anesth. 2001;15(3):288–92.

    Article  PubMed  CAS  Google Scholar 

  98. Cardiothoracic Surgery, University of Southern California, Keck School of Medicine. A patient guide to pain management and medication after heart surgery.

    Google Scholar 

  99. Karmakar M. Thoracic paravertebral block: review article. Anesthesiology. 2001;95(3):771–80.

    Article  PubMed  CAS  Google Scholar 

  100. Joshi G, Bonnet F, Shah R, et al. A systematic review of randomized trials evaluating regional techniques for postthoracotomy analgesia. Anesth Analg. 2008;107:1026–40.

    Article  PubMed  CAS  Google Scholar 

  101. ChasseryC. Thoracic surgery as a model for postoperative acute and chronic pain. Anesthesiology Rounds. 2007;6(1): as presented in the Department of Anesthesiology, Faculty of Medicine , University of Montreal, www.anesthesiologyrounds.ca.

  102. Gottschalk A, Smith D. New concepts in acute pain therapy: preemptive analgesia. Am Fam Physician. 2001;63(10):1979–84. (www.aafp.org/afp).

  103. Kehlet H, Dahl JB. The value of “multimodal” or “balanced analgesia” in postoperative pain treatment. Anesth Analg. 1993;77:1049.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jack M. Berger .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Berger, J.M., Ayoub, T., Patel, J. (2011). Acute Pain Control in Geriatric Patients After Cardiac and Thoracic Surgeries. In: Katlic, M. (eds) Cardiothoracic Surgery in the Elderly. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0892-6_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-0892-6_9

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0891-9

  • Online ISBN: 978-1-4419-0892-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics