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Multiple Endocrine Neoplasia Type 2: Clinical Manifestations and Management

  • Amber L. Traugott
  • Jeffrey F. Moley
Chapter
Part of the Cancer Treatment and Research book series (CTAR, volume 153)

Abstract

In the 1950s and 1960s, an increasing association was reported between medullary thyroid carcinoma (MTC) and pheochromocytoma, two relatively rare conditions. Identification of kindreds affected by the constellation of MTC, pheochromocytoma, and hyperparathyroidism led to the recognition of multiple endocrine neoplasia type 2 (MEN-2) as a distinct syndrome in the 1960s [1]. Three distinct, but related, MEN-2 syndromes are now recognized: MEN-2A, MEN-2B, and familial medullary thyroid carcinoma (FMTC).

Keywords

Medullary Thyroid Carcinoma Calcitonin Level Central Lymph Node Dissection Familial Medullary Thyroid Carcinoma Sporadic Medullary Thyroid Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Endocrine and Oncologic Surgery SectionWashington University School of MedicineSt. LouisUSA

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