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Introduction

  • Olimpia Meucci
Chapter

Abstract

During the last two decades chemokine receptors have consistently been in the spotlight albeit for different reasons. They have “evolved” from coordinators of inflammatory/immune responses to HIV co-receptors, mediators of organogenesis and development, cancer metastases inducers, and neuromodulators. However, it seems that our knowledge of the physiological and pathological roles of this large subfamily of G-protein-coupled receptors has not yet reached a plateau. Novel and essential biological functions of chemokine receptors are continuously been discovered and each of these new discoveries has led to alternative therapeutic strategies that show promise in the treatment of several pathologies, including AIDS and AIDS-related conditions.

Keywords

Chemokine Receptor Opioid Receptor Drug Abuser Cognitive Disorder Alternative Therapeutic Strategy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Departments of Pharmacology and Physiology & Institute of Molecular Medicine and Infectious DiseaseDrexel University College of MedicinePhiladelphiaUSA

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