Personalized Therapy of Cardiovascular Diseases



The constantly growing volume of available data on cardiovascular disorders will require an organized interpretation of variations in DNA and mRNA as well as proteins, both on the individual and the population levels. A five-step strategy can be followed when trying to identify genes and gene products involved in differential responses to cardiovascular drugs (Siest et al. 2007): Pharmacokinetic-related genes and phenotypes Pharmacodynamic targets, genes, and products Cardiovascular diseases and risks depending on specific or large metabolic cycles Physiological variations of previously identified genes and proteins Environmental influences on them


Heart Attack Sudden Cardiac Death Isosorbide Dinitrate Target Cell Membrane SLCO1B1 Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Jain PharmaBiotechBaselSwitzerland

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